Technology Process of 4-(3,5-dihydroxyphenyl)-1-bromobutane
There total 5 articles about 4-(3,5-dihydroxyphenyl)-1-bromobutane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: diethyl ether / 23 h / 20 °C / Inert atmosphere; Cooling with ice
2: hexane; toluene / 4.5 h / 40 °C
3: dihydrogen peroxide; sodium hydroxide / water; toluene
4: carbon tetrabromide; triphenylphosphine / acetonitrile / 1 h / 20 °C / Cooling with ice
5: boron tribromide / dichloromethane; 1,2-dichloro-ethane / 1.5 h / Reflux
With
carbon tetrabromide; dihydrogen peroxide; boron tribromide; triphenylphosphine; sodium hydroxide;
In
diethyl ether; hexane; dichloromethane; water; 1,2-dichloro-ethane; toluene; acetonitrile;
DOI:10.1002/jlcr.1840
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dihydrogen peroxide; sodium hydroxide / water; toluene
2: carbon tetrabromide; triphenylphosphine / acetonitrile / 1 h / 20 °C / Cooling with ice
3: boron tribromide / dichloromethane; 1,2-dichloro-ethane / 1.5 h / Reflux
With
carbon tetrabromide; dihydrogen peroxide; boron tribromide; triphenylphosphine; sodium hydroxide;
In
dichloromethane; water; 1,2-dichloro-ethane; toluene; acetonitrile;
DOI:10.1002/jlcr.1840
- Guidance literature:
-
Multi-step reaction with 2 steps
1: carbon tetrabromide; triphenylphosphine / acetonitrile / 1 h / 20 °C / Cooling with ice
2: boron tribromide / dichloromethane; 1,2-dichloro-ethane / 1.5 h / Reflux
With
carbon tetrabromide; boron tribromide; triphenylphosphine;
In
dichloromethane; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1002/jlcr.1840
