5-acetamido-4-azido-2,6-anhydro-3,4,5-trideoxy-6-((2-phenylhydrazinyl)methyl)-L-gluco-hex-2-enonic acid

Base Information

• Chemical Name: 5-acetamido-4-azido-2,6-anhydro-3,4,5-trideoxy-6-((2-phenylhydrazinyl)methyl)-L-gluco-hex-2-enonic acid
• CAS No.: 1428441-33-1
• Molecular Formula: C₁₅H₁₈N₆O₄
• Molecular Weight: 346.346
• Mol file: 1428441-33-1.mol

Synonyms:

Chemical Property of 5-acetamido-4-azido-2,6-anhydro-3,4,5-trideoxy-6-((2-phenylhydrazinyl)methyl)-L-gluco-hex-2-enonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-acetamido-4-azido-2,6-anhydro-3,4,5-trideoxy-6-((2-phenylhydrazinyl)methyl)-L-gluco-hex-2-enonic acid

There total 4 articles about 5-acetamido-4-azido-2,6-anhydro-3,4,5-trideoxy-6-((2-phenylhydrazinyl)methyl)-L-gluco-hex-2-enonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H20N6O4 → 5-acetamido-4-azido-2,6-anhydro-3,4,5-trideoxy-6-((2-phenylhydrazinyl)methyl)-L-gluco-hex-2-enonic acid (1428441-33-1)

Guidance literature:

With lithium hydroxide; In methanol; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jm301892f

Reference yield:

phenylhydrazine (100-63-0) → 5-acetamido-4-azido-2,6-anhydro-3,4,5-trideoxy-6-((2-phenylhydrazinyl)methyl)-L-gluco-hex-2-enonic acid (1428441-33-1)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid / methanol / Inert atmosphere

2: sodium cyanoborohydride / Inert atmosphere

3: lithium hydroxide / methanol / 1 h / 20 °C / Inert atmosphere

With sodium cyanoborohydride; acetic acid; lithium hydroxide; In methanol;

DOI:10.1021/jm301892f

Reference yield:

5-acetamido-2,6-anhydro-4-azido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid methyl ester (152178-79-5) → 5-acetamido-4-azido-2,6-anhydro-3,4,5-trideoxy-6-((2-phenylhydrazinyl)methyl)-L-gluco-hex-2-enonic acid (1428441-33-1)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium periodate / methanol; water / 0.5 h / 20 °C

2: acetic acid / methanol / Inert atmosphere

3: sodium cyanoborohydride / Inert atmosphere

4: lithium hydroxide / methanol / 1 h / 20 °C / Inert atmosphere

With sodium periodate; sodium cyanoborohydride; acetic acid; lithium hydroxide; In methanol; water;

DOI:10.1021/jm301892f

upstream raw materials:

phenylhydrazine

5-acetamido-2,6-anhydro-4-azido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid methyl ester