C₃₃H₃₈N₂O₇

Base Information

• Chemical Name: C₃₃H₃₈N₂O₇
• CAS No.: 1593269-73-8
• Molecular Formula: C₃₃H₃₈N₂O₇
• Molecular Weight: 574.674
• Mol file: 1593269-73-8.mol

Synonyms:

Chemical Property of C₃₃H₃₈N₂O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₃₈N₂O₇

There total 3 articles about C₃₃H₃₈N₂O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 4-{[{4-[(1-tert-butoxy-2-methyl-1-oxopropan-2yl) oxy]-3,5-dimethylbenzyl}(furan-2-ylmethyl) amino] methyl}-2-phenyl-1,3-oxazole-5-carboxylate (1593269-72-7) → C33H38N2O7 (1593269-73-8)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; at 20 - 50 ℃; for 73.5h;

DOI:10.1248/cpb.c13-00513

Reference yield:

ethyl 4-(bromomethyl)-2-phenyl-1,3-oxazole-5-carboxylate (189271-78-1) → C33H38N2O7 (1593269-73-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 40 °C

2: sodium hydroxide / tetrahydrofuran; water / 73.5 h / 20 - 50 °C

With potassium carbonate; sodium hydroxide; In tetrahydrofuran; water; N,N-dimethyl-formamide;

DOI:10.1248/cpb.c13-00513

Reference yield:

Ethyl 4-methyl-2-phenyloxazole-5-carboxylate (4620-52-4) → C33H38N2O7 (1593269-73-8)

Guidance literature:

Multi-step reaction with 3 steps

1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 40 °C

3: sodium hydroxide / tetrahydrofuran; water / 73.5 h / 20 - 50 °C

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate; sodium hydroxide; In tetrahydrofuran; tetrachloromethane; water; N,N-dimethyl-formamide;

DOI:10.1248/cpb.c13-00513

upstream raw materials:

ethyl 4-(bromomethyl)-2-phenyl-1,3-oxazole-5-carboxylate

ethyl 4-{[{4-[(1-tert-butoxy-2-methyl-1-oxopropan-2yl) oxy]-3,5-dimethylbenzyl}(furan-2-ylmethyl) amino] methyl}-2-phenyl-1,3-oxazole-5-carboxylate

Ethyl 4-methyl-2-phenyloxazole-5-carboxylate

Downstream raw materials:

tert-butyl 2-(4-{[{[2-phenyl-5-(hydroxymethyl)-1,3-oxazol-4-yl]methyl}(furan-2-ylmethyl)amino]methyl}-2,6-dimethylphenoxy)-2-methylpropanoate

2-(4-{[{[2-phenyl-5-(dimethylcarbamoyl)-1,3-oxazol-4-yl] methyl}(furan-2-ylmethyl) amino] methyl}-2,6-dimethylphenoxy)-2-methylpropanoic acid

2-(4-{[{[2-phenyl-5-(hydroxymethyl)-1,3-oxazol-4-yl]-methyl}(furan-2-ylmethyl) amino] methyl}-2,6-dimethylphenoxy)-2-methylpropanoic acid

tert-butyl 2-(4-{[{[2-phenyl-5-(dimethylcarbamoyl)-1,3-oxazol-4-yl]methyl}(furan-2-ylmethyl)amino]methyl}-2,6-dimethylphenoxy)-2-methylpropanoate