Technology Process of C14H12N2O3
There total 4 articles about C14H12N2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); copper;
In
dimethyl sulfoxide;
Heating;
DOI:10.1021/jo302132d
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / acetonitrile / 16 h / 18 °C
2: lithium chloride; water / dimethyl sulfoxide / 140 °C
3: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; toluene-4-sulfonic acid / dimethyl sulfoxide; toluene / 55 °C
4: iodine; pyridine / chloroform / 18 °C
5: tris-(dibenzylideneacetone)dipalladium(0); copper / dimethyl sulfoxide / Heating
With
pyridine; tris-(dibenzylideneacetone)dipalladium(0); water; iodine; copper; potassium carbonate; toluene-4-sulfonic acid; lithium chloride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
chloroform; dimethyl sulfoxide; toluene; acetonitrile;
1: |Michael Addition / 5: |Ullmann Condensation;
DOI:10.1021/jo302132d
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; toluene-4-sulfonic acid / dimethyl sulfoxide; toluene / 55 °C
2: iodine; pyridine / chloroform / 18 °C
3: tris-(dibenzylideneacetone)dipalladium(0); copper / dimethyl sulfoxide / Heating
With
pyridine; tris-(dibenzylideneacetone)dipalladium(0); iodine; copper; toluene-4-sulfonic acid; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
chloroform; dimethyl sulfoxide; toluene;
3: |Ullmann Condensation;
DOI:10.1021/jo302132d
