N-(2-chlorophenyl)-N-(phenylsulfonyl)glycine

Base Information

• Chemical Name: N-(2-chlorophenyl)-N-(phenylsulfonyl)glycine
• CAS No.: 117309-39-4
• Molecular Formula: C₁₄H₁₂ClNO₄S
• Molecular Weight: 325.773
• NSC Number: 626990
• DSSTox Substance ID: DTXSID001256834
• ChEMBL ID: CHEMBL37193
• Mol file: 117309-39-4.mol

Synonyms:N-(2-chlorophenyl)-N-(phenylsulfonyl)glycine;117309-39-4;CHEMBL37193;2-[N-(benzenesulfonyl)-2-chloroanilino]acetic acid;NSC626990;(2-Chloro(phenylsulfonyl)anilino)acetic acid;Oprea1_648331;[Benzenesulfonyl-(2-chloro-phenyl)-amino]-acetic acid;DTXSID001256834;BDBM50016593;MFCD01964850;STK113560;AKOS000610559;NSC-626990;CS-0335155;SR-01000355770;2-[N-(2-chlorophenyl)benzenesulfonamido]acetic acid;SR-01000355770-1;2-[N-(benzenesulfonyl)-2-chloro-anilino]acetic acid

Chemical Property of N-(2-chlorophenyl)-N-(phenylsulfonyl)glycine

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 325.0175567
• Heavy Atom Count: 21
• Complexity: 456

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)S(=O)(=O)N(CC(=O)O)C2=CC=CC=C2Cl

Technology Process of N-(2-chlorophenyl)-N-(phenylsulfonyl)glycine

There total 2 articles about N-(2-chlorophenyl)-N-(phenylsulfonyl)glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[Benzenesulfonyl-(2-chloro-phenyl)-amino]-acetic acid ethyl ester → [Benzenesulfonyl-(2-chloro-phenyl)-amino]-acetic acid (117309-39-4)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 2h; Yield given; Heating;

DOI:10.1021/jm00121a027

Reference yield:

2-chloro-1-(benzenesulfonylamino)benzene (21226-30-2) → [Benzenesulfonyl-(2-chloro-phenyl)-amino]-acetic acid (117309-39-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) NaH / 1) DMF, room temperature, 30 min.; 2) room temperature, overnight

2: NaOH / ethanol; H₂O / 2 h / Heating

With sodium hydroxide; sodium hydride; In ethanol; water;

DOI:10.1021/jm00121a027

upstream raw materials:

2-chloro-1-(benzenesulfonylamino)benzene