(S)-Ketoprofenoyl-CoA

Base Information

• Chemical Name: (S)-Ketoprofenoyl-CoA
• CAS No.: 430438-75-8
• Molecular Formula: C₃₇H₄₈N₇O₁₈P₃S
• Molecular Weight: 1003.81
• Mol file: 430438-75-8.mol

Synonyms:

Chemical Property of (S)-Ketoprofenoyl-CoA

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-Ketoprofenoyl-CoA

There total 4 articles about (S)-Ketoprofenoyl-CoA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

coenzyme A trilithium salt + (S)-1-(2-(3-benzoylphenyl)propanoyl)imidazole (709040-07-3) → (S)-Ketoprofenoyl-CoA (430438-75-8)

Guidance literature:

coenzyme A trilithium salt; (S)-1-(2-(3-benzoylphenyl)propanoyl)imidazole; With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20 ℃; for 16h;

pH=4 - 5;

DOI:10.1039/c1cc10763a

Reference yield:

ketoprofen (22071-15-4,22161-86-0) → (S)-Ketoprofenoyl-CoA (430438-75-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: dichloromethane / 1 h / 20 °C / Inert atmosphere

2.1: sodium hydrogencarbonate / tetrahydrofuran; water / 16 h / 20 °C

2.2: dowex X₅₀ / pH 4 - 5

With sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane; water;

DOI:10.1039/c1cc10763a

Reference yield:

ketoprofen (22071-15-4,22161-86-0) + coenzyme A (85-61-0) → (S)-Ketoprofenoyl-CoA (430438-75-8) + (R)-Ketoprofenoyl-CoA (430438-74-7)

Guidance literature:

With recombinant luciferase from Pyrocoelia miyako, firefly; ATP; enantioselective reaction; aq. buffer; Enzymatic reaction;

DOI:10.1271/bbb.110299

upstream raw materials:

(S)-1-(2-(3-benzoylphenyl)propanoyl)imidazole

ketoprofen

S-ketoprofen

coenzyme A