Piperazine, 1-[(3,4-dimethoxyphenyl)acetyl]-

Base Information

Chemical Name:Piperazine, 1-[(3,4-dimethoxyphenyl)acetyl]-
CAS No.:139329-73-0
Molecular Formula:C14H20N2O3
Molecular Weight:264.324
Hs Code.:
DSSTox Substance ID:DTXSID60469154
Wikidata:Q82296746

Synonyms:139329-73-0;Piperazine, 1-[(3,4-dimethoxyphenyl)acetyl]-;DTXSID60469154;AKOS000155529

Suppliers and Price of Piperazine, 1-[(3,4-dimethoxyphenyl)acetyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Piperazine, 1-[(3,4-dimethoxyphenyl)acetyl]-

Chemical Property:

XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:264.14739250
Heavy Atom Count:19
Complexity:292

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CC(=O)N2CCNCC2)OC

Technology Process of Piperazine, 1-[(3,4-dimethoxyphenyl)acetyl]-

There total 2 articles about Piperazine, 1-[(3,4-dimethoxyphenyl)acetyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.9%

: 110-85-0
piperazine

: 10313-60-7
3,4-dimethoxyphenylacetyl chloride

: 139329-73-0
1-(3,4-dimethoxyphenylacetyl)piperazine

Guidance literature:: With sodium hydroxide; In chloroform; at 20 ℃; for 0.5h;
DOI:10.1248/cpb.54.470

Reference yield:

: 93-40-3
(3,4-Dimethoxyphenyl)acetic acid

: 139329-73-0
1-(3,4-dimethoxyphenylacetyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / tetrahydrofuran / 2 h / Heating

2: 77.9 percent / aq. NaOH / CHCl₃ / 0.5 h / 20 °C

With sodium hydroxide; thionyl chloride; In tetrahydrofuran; chloroform;
DOI:10.1248/cpb.54.470