Methylconiine, (R)-

Base Information

Chemical Name:Methylconiine, (R)-
CAS No.:6032-02-6
Molecular Formula:C₉H₁₉N
Molecular Weight:141.257
Hs Code.:
UNII:O8S29QK9FX
Nikkaji Number:J785.145F

Synonyms:(-)-N-Methylconiine;Methylconiine, (R)-;Methylconiine L-form [MI];O8S29QK9FX;UNII-O8S29QK9FX;Piperidine, 1-methyl-2-propyl-, (R)-;Piperidine, 1-methyl-2-propyl-, (2R)-;6032-02-6;(?)-Methylconiine

Suppliers and Price of Methylconiine, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of Methylconiine, (R)-

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:141.151749610
Heavy Atom Count:10
Complexity:90.7

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCC1CCCCN1C
Isomeric SMILES:CCC[C@@H]1CCCCN1C

Technology Process of Methylconiine, (R)-

There total 12 articles about Methylconiine, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-Allyl-4-hydroxy-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid 1-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester 3-methyl ester

: 6032-02-6,553-75-3,92701-56-9
(-)-N-methylconiine

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / H₂O, NaCl / dimethylsulfoxide

2: 87 percent / BF₃*Et₂O

3: 90 percent / H₂ / Raney Ni

4: LiAlH₄

With lithium aluminium tetrahydride; boron trifluoride diethyl etherate; water; hydrogen; sodium chloride; nickel; In dimethyl sulfoxide;
DOI:10.1055/s-1999-2623

Reference yield:

: 2-Allyl-4-hydroxy-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid bis-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester

: 6032-02-6,553-75-3,92701-56-9
(-)-N-methylconiine

Guidance literature:: Multi-step reaction with 5 steps

1: 74 percent / 140 °C

2: 80 percent / H₂O, NaCl / dimethylsulfoxide

3: 87 percent / BF₃*Et₂O

4: 90 percent / H₂ / Raney Ni

5: LiAlH₄

With lithium aluminium tetrahydride; boron trifluoride diethyl etherate; water; hydrogen; sodium chloride; nickel; In dimethyl sulfoxide;
DOI:10.1055/s-1999-2623

Reference yield:

: 186045-52-3
4-Oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-naphthalen-2-yl-ethyl)-cyclohexyl ester

: 6032-02-6,553-75-3,92701-56-9
(-)-N-methylconiine

Guidance literature:: Multi-step reaction with 4 steps

1: TiCl₄ / CH₂Cl₂ / -30 °C

2: 88 percent / BF₃*Et₂O

3: H₂ / Raney Ni

4: LiAlH₄

With lithium aluminium tetrahydride; boron trifluoride diethyl etherate; hydrogen; titanium tetrachloride; nickel; In dichloromethane;
DOI:10.1016/S0040-4039(96)02129-6