Technology Process of Furo[2,3-c]pyridine-2-carbonyl chloride (9CI)
There total 7 articles about Furo[2,3-c]pyridine-2-carbonyl chloride (9CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
thionyl chloride;
In
N,N-dimethyl-formamide;
at 85 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sulfuric acid / 72 h / Reflux
2: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 16 h / -10 - 20 °C
3: sodium hydride / tetrahydrofuran; mineral oil / 16 h / 0 - 20 °C / Inert atmosphere
4: pyridine / dichloromethane / 16 h / 0 - 20 °C
5: palladium 10% on activated carbon; triethylamine; hydrogen / ethanol / 16 h / 760.05 Torr
6: potassium hydroxide; water / tetrahydrofuran; methanol / 16 h / 20 °C
7: thionyl chloride / N,N-dimethyl-formamide / 2 h / 85 °C
With
pyridine; thionyl chloride; di-isopropyl azodicarboxylate; sulfuric acid; palladium 10% on activated carbon; water; hydrogen; sodium hydride; triethylamine; triphenylphosphine; potassium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 16 h / -10 - 20 °C
2: sodium hydride / tetrahydrofuran; mineral oil / 16 h / 0 - 20 °C / Inert atmosphere
3: pyridine / dichloromethane / 16 h / 0 - 20 °C
4: palladium 10% on activated carbon; triethylamine; hydrogen / ethanol / 16 h / 760.05 Torr
5: potassium hydroxide; water / tetrahydrofuran; methanol / 16 h / 20 °C
6: thionyl chloride / N,N-dimethyl-formamide / 2 h / 85 °C
With
pyridine; thionyl chloride; di-isopropyl azodicarboxylate; palladium 10% on activated carbon; water; hydrogen; sodium hydride; triethylamine; triphenylphosphine; potassium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;
