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Furo[2,3-c]pyridine-2-carboxylic acid is a heterocyclic compound characterized by a furan ring fused to a pyridine ring, featuring a carboxylic acid functional group at the 2-position of the pyridine. This synthetic compound is not found naturally and is recognized for its potential biological and pharmacological properties, making it a promising candidate for drug development and research applications.

112372-15-3

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112372-15-3 Usage

Uses

Used in Pharmaceutical Research:
Furo[2,3-c]pyridine-2-carboxylic acid serves as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups contribute to its potential as a drug candidate for therapeutic uses, particularly in the development of anti-inflammatory and antimicrobial agents.
Used in Chemical Synthesis:
Furo[2,3-c]pyridine-2-carboxylic acid's distinctive molecular architecture positions it as a valuable target for chemical synthesis, where it can be further modified or used as a building block to create novel molecules with specific biological activities.
Used in Drug Development:
Furo[2,3-c]pyridine-2-carboxylic acid is utilized in drug development to explore its potential as a lead compound for new medications. Its pharmacological properties are under investigation for various applications, including the treatment of inflammatory conditions and infectious diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 112372-15-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,3,7 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 112372-15:
(8*1)+(7*1)+(6*2)+(5*3)+(4*7)+(3*2)+(2*1)+(1*5)=83
83 % 10 = 3
So 112372-15-3 is a valid CAS Registry Number.

112372-15-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Furo[2,3-c]pyridine-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names QC-5056

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112372-15-3 SDS

112372-15-3Relevant articles and documents

AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES

-

, (2013/09/12)

The present invention relates to certain amido-benzyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

PYRIDINYL AND PYRIMIDINYL SULFOXIDE AND SULFONE DERIVATIVES

-

, (2013/09/12)

Disclosed are certain pyridinyl and pyrimidinyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds and methods of treatment using such compounds.

AMIDO SPIROCYCLIC AMIDE AND SULFONAMIDE DERIVATIVES

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, (2013/09/12)

Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

AMIDO-BENZYL SULFONE AND SULFONAMIDE DERIVATIVES

-

, (2013/09/12)

Disclosed are certain amido-benzyl sulfone and sulfonamide compounds, pharmaceutical compositions comprising such compounds, land methods of treatment using such compounds.

AMIDO-BENZYL SULFOXIDE DERIVATIVES

-

, (2013/09/12)

The present invention relates to certain amido-benzyl sulfoxide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment of an NAMPT-mediated disease or condition in a subject, selected from solid or liquid tumor, rheumat

ALKYL-AND DI-SUBSTITUTED AMIDO-BENZYL SULFONAMIDE DERIVATIVES

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, (2013/09/12)

The present invention relates to certain alkyl- and di-substituted amido-benzyl sulfonamide compounds, pharmaceutical compositions comprising such compounds, and to methods of treatment of NAMPT-mediated disorders, such as diabetes, rheumatoid arthritis,

NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT

-

Page/Page column 400-401, (2012/03/26)

The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:

Quinuclidines-substituted-multi-cyclic-heteroaryls for the treatment of disease

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, (2008/06/13)

The invention provides compounds of Formula I: 1where in W is 2These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful to treat diseases or conditions in which α7 is known to be involved.

Furopyridines. VII. Preparation and Hydrolysis of 2-Cyano and 3-Cyano Derivatives of Furo-, Furo-, and Furopyridine

Morita, Hiroyuki,Shiotani, Shunsaku

, p. 373 - 376 (2007/10/02)

This paper describes the preparation and hydrolysis of 2-cyano and 3-cyano derivatives of furo-, furo-, and furopyridine.Treatment of furopyridines 1a, 1b and 1c with n-butyllithium in hexane-tetrahydrofuran at -70 deg C and subsequent addition of N,N-dimethylformamide yielded 2-formyl derivatives 2a, 2b and 2c.Dehydration of the oximes 4a, 4b and 4c of 2a, 2b and 2c gave 2-cyano compounds 5a, 5b and 5c, which were hydrolyzed to give 2-carboxylic acids, 6a, 6b and 6c, respectively.Reaction of 3-bromo compounds 7a, 7b and 7c with copper(I) cyanide in N,N-dimethylformamide afforded 3-cyano derivatives 8a, 8b and 8c.Alkaline hydrolysis of 8a, 8b and 8c gave compounds formed by fission of the 1-2 bond of furopyridines 9a, 9b and 9c, while acidic hydrolysis gave the corresponding carboxamides, 10a, 10b and 10c.

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