Technology Process of rac-5-(4-chlorophenyl)-2,2-dimethyloxazolidine
There total 4 articles about rac-5-(4-chlorophenyl)-2,2-dimethyloxazolidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-amino-1-(4-chlorophenyl)ethanol; acetone;
In
benzene;
at 33 - 35 ℃;
In
benzene;
Reflux;
DOI:10.1515/hc-2013-0042
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / methanol / 1.25 h / 5 - 20 °C / Green chemistry
2: hydrogen; magnesium sulfate; sodium hydroxide / water; isopropyl alcohol; aq. phosphate buffer / 4 h / 30 °C / 7500.75 Torr / pH 7 / Green chemistry
3: magnesium sulfate / 3 h / 30 °C / Green chemistry
With
sodium tetrahydroborate; hydrogen; magnesium sulfate; sodium hydroxide;
In
methanol; aq. phosphate buffer; water; isopropyl alcohol;
DOI:10.1039/c3gc41666f
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen; magnesium sulfate; sodium hydroxide / water; isopropyl alcohol; aq. phosphate buffer / 4 h / 30 °C / 7500.75 Torr / pH 7 / Green chemistry
2: magnesium sulfate / 3 h / 30 °C / Green chemistry
With
hydrogen; magnesium sulfate; sodium hydroxide;
In
aq. phosphate buffer; water; isopropyl alcohol;
DOI:10.1039/c3gc41666f
