3',6'-dichlorohydrofluoran acid methyl ester

Base Information

• Chemical Name: 3',6'-dichlorohydrofluoran acid methyl ester
• CAS No.: 87021-20-3
• Molecular Formula: C₂₁H₁₄Cl₂O₃
• Molecular Weight: 385.246
• Mol file: 87021-20-3.mol

Synonyms:

Chemical Property of 3',6'-dichlorohydrofluoran acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3',6'-dichlorohydrofluoran acid methyl ester

There total 4 articles about 3',6'-dichlorohydrofluoran acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

methanol (67-56-1) + 3,6-dichloro-9-(carboxyphenyl)xanthen (87021-19-0) → 3',6'-dichlorohydrofluoran acid methyl ester (87021-20-3)

Guidance literature:

With sulfuric acid; for 9h; Heating;

Reference yield:

3-monochlorophenol (108-43-0) → 3',6'-dichlorohydrofluoran acid methyl ester (87021-20-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 76 percent / ZnCl₂ / 12 h / 155 - 160 °C

2: 97 percent / ZnCl₂, 80percent aq. AcOH / 10 h / Heating

3: 75 percent / conc. H₂SO₄ / 9 h / Heating

With sulfuric acid; acetic acid; zinc(II) chloride;

Reference yield:

2-(4'-chloro-2'-hydroxybenzoyl)benzoic acid (76135-38-1) → 3',6'-dichlorohydrofluoran acid methyl ester (87021-20-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 76 percent / ZnCl₂ / 12 h / 155 - 160 °C

2: 97 percent / ZnCl₂, 80percent aq. AcOH / 10 h / Heating

3: 75 percent / conc. H₂SO₄ / 9 h / Heating

With sulfuric acid; acetic acid; zinc(II) chloride;

upstream raw materials:

methanol

3,6-dichloro-9-(carboxyphenyl)xanthen

3-monochlorophenol

3',6'-dichloro-spiro[phthalan-1,9'-xanthen]-3-one