C₃₈H₅₂NOPS

Base Information

• Chemical Name: C₃₈H₅₂NOPS
• CAS No.: 2509201-09-4
• Molecular Formula: C₃₈H₅₂NOPS
• Molecular Weight: 601.877
• Mol file: 2509201-09-4.mol

Synonyms:

Chemical Property of C₃₈H₅₂NOPS

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₈H₅₂NOPS

There total 6 articles about C₃₈H₅₂NOPS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C37H50NOPS + methyl iodide (74-88-4) → C38H52NOPS (2413724-69-1,2509201-09-4)

Guidance literature:

C₃₇H₅₀NOPS; With n-butyllithium; In tetrahydrofuran; at -30 ℃; for 1.5h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; at -50 - 0 ℃; Inert atmosphere;

DOI:10.1002/anie.201912408

Reference yield:

ortho-bromobenzaldehyde (6630-33-7) → C38H52NOPS (2413724-69-1,2509201-09-4)

Guidance literature:

Multi-step reaction with 6 steps

1.1: toluene-4-sulfonic acid / toluene / 16 h / 150 °C / Inert atmosphere; Dean-Stark

2.1: sodium t-butanolate; palladium diacetate; 1,1'-bis-(diphenylphosphino)ferrocene / toluene / 10 h / 110 °C / Inert atmosphere

3.1: sulfuric acid / water; tetrahydrofuran / 1.5 h / 60 °C / Inert atmosphere

4.1: titanium tetraalkoxide / tetrahydrofuran / 12 h / 50 °C / Inert atmosphere

5.1: tetrahydrofuran / -78 - 20 °C / Inert atmosphere

6.1: n-butyllithium / tetrahydrofuran / 1.5 h / -30 °C / Inert atmosphere

6.2: -50 - 0 °C / Inert atmosphere

With 1,1'-bis-(diphenylphosphino)ferrocene; n-butyllithium; sulfuric acid; palladium diacetate; toluene-4-sulfonic acid; sodium t-butanolate; In tetrahydrofuran; water; toluene;

DOI:10.1002/anie.201912408

Reference yield:

C29H39O2P → C38H52NOPS (2413724-69-1,2509201-09-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sulfuric acid / water; tetrahydrofuran / 1.5 h / 60 °C / Inert atmosphere

2.1: titanium tetraalkoxide / tetrahydrofuran / 12 h / 50 °C / Inert atmosphere

3.1: tetrahydrofuran / -78 - 20 °C / Inert atmosphere

4.1: n-butyllithium / tetrahydrofuran / 1.5 h / -30 °C / Inert atmosphere

4.2: -50 - 0 °C / Inert atmosphere

With n-butyllithium; sulfuric acid; In tetrahydrofuran; water;

DOI:10.1002/anie.201912408

upstream raw materials:

phenylmagnesium bromide

methyl iodide

ortho-bromobenzaldehyde

2-(2-bromophenyl)-1,3-dioxolan