2-[[2-(Phenylamino)-4-quinazolinyl]oxy]acetic acid hydrazide

Base Information

Chemical Name:2-[[2-(Phenylamino)-4-quinazolinyl]oxy]acetic acid hydrazide
CAS No.:154136-65-9
Molecular Formula:C₁₆H₁₅N₅O₂
Molecular Weight:309.327
Hs Code.:
DSSTox Substance ID:DTXSID601183932

Synonyms:2-[[2-(Phenylamino)-4-quinazolinyl]oxy]acetic acid hydrazide;DTXSID601183932;154136-65-9

Suppliers and Price of 2-[[2-(Phenylamino)-4-quinazolinyl]oxy]acetic acid hydrazide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[[2-(Phenylamino)-4-quinazolinyl]oxy]acetic acid hydrazide

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:309.12257474
Heavy Atom Count:23
Complexity:389

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC2=NC3=CC=CC=C3C(=N2)OCC(=O)NN

Technology Process of 2-[[2-(Phenylamino)-4-quinazolinyl]oxy]acetic acid hydrazide

There total 3 articles about 2-[[2-(Phenylamino)-4-quinazolinyl]oxy]acetic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 148063-17-6
4-carbethoxymethoxy-2-(N-phenylamino)quinazoline

: 154136-65-9
2-(N-phenylamino)quinazolin-4-yloxoacetylhydrazine

Guidance literature:: With hydrazine hydrate; In ethanol; for 6h; Heating;

Reference yield:

: 1026-16-0
2-(phenylamino)-4H-benzo[d][1,3]oxazin-4-one

: 154136-65-9
2-(N-phenylamino)quinazolin-4-yloxoacetylhydrazine

Guidance literature:: Multi-step reaction with 3 steps

1: 50 percent / formamide / 3 h / 150 °C

2: 63 percent / K₂CO₃ / acetone / 24 h / Heating

3: 58 percent / NH₂NH₂*H₂O / ethanol / 6 h / Heating

With potassium carbonate; hydrazine hydrate; formamide; In ethanol; acetone;

Reference yield:

: 4248-15-1
2-anilinoquinazolin-4(3H)-one

: 154136-65-9
2-(N-phenylamino)quinazolin-4-yloxoacetylhydrazine

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / K₂CO₃ / acetone / 24 h / Heating

2: 58 percent / NH₂NH₂*H₂O / ethanol / 6 h / Heating

With potassium carbonate; hydrazine hydrate; In ethanol; acetone;