1026-16-0

Basic information

• Product Name: 2-Anilino-4H-3,1-benzoxazin-4-one
• Synonyms: 2-Anilino-4H-3,1-benzoxazin-4-one;2-(PHENYLAMINO)-4H-3,1-BENZOXAZIN-4-ONE
• CAS NO: 1026-16-0
• Molecular Formula: C₁₄H₁₀N₂O₂
• Molecular Weight: 238.245
• Mol File: 1026-16-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Anilino-4H-3,1-benzoxazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Anilino-4H-3,1-benzoxazin-4-one(1026-16-0)
• EPA Substance Registry System: 2-Anilino-4H-3,1-benzoxazin-4-one(1026-16-0)

Safety Data

• Hazardous Substances Data: 1026-16-0(Hazardous Substances Data)

Usage

Chemical structure

A benzoxazinone derivative with an aniline group attached to the 2-position and a ketone group at the 4-position.

Natural occurrence

Found in plants such as corn and wheat, and is also known as DIBOA (2,4-dihydroxy-1,4-benzoxazin-3-one).

Biological activities

Has potential as an allelopathic agent, anti-inflammatory and antioxidant properties, and as an anti-cancer agent.

Pharmaceutical applications

Being investigated for its potential in the development of pharmaceutical drugs.

Research areas

Chemistry, biochemistry, and pharmacology.

Upstream product

• 103-71-9 phenyl isocyanate 
• 615-36-1 2-bromoaniline 
• 13939-06-5 molybdenum hexacarbonyl 
• 1592-00-3 2-bromophenyl isocyanate 
• 62-53-3 aniline 
• 118-92-3 anthranilic acid 
• 4426-68-0 phenyl isoselenocyanate 
• 615-43-0 2-iodophenylamine 
• 201230-82-2 carbon monoxide 
• 54467-95-7 1-azido-2-iodo-benzene 
• 13114-91-5 1-(2-bromophenyl)-3-phenylurea 
• 134-20-3 2-carbomethoxyaniline 
• 2321-50-8 methyl 2-(3-phenylureido)benzoate 
• 2164-95-6 N-phenyl-N'-(2-carboxyphenyl)-urea 

Downstream Products

• 86-96-4 1,2,3,4-tetrahydro-quinazoline-2,4-dione 
• 94775-15-2 3-Benzalamino-(1H,3H)-quinazolin-2,4-dione 
• 154136-78-4 5-<2'-(N-phenylamino)quinazolin-4'-yloxomethyl>-2-chloroacetyl-4-phenyl-1,2,4-triazole-3-thione 
• 154136-69-3 5-<2'-(N-phenylamino)quinazolin-4'-yloxomethyl>-4-phenyl-3-thioureido-1,2,4-triazole 
• 154136-66-0 5-<2'-(N-phenylamino)quinazolin-4'-yloxomethyl>-4-phenyl-1,2,4-triazole-3-thiol 
• 148063-17-6 4-carbethoxymethoxy-2-(N-phenylamino)quinazoline 
• 154136-65-9 2-(N-phenylamino)quinazolin-4-yloxoacetylhydrazine 
• 94775-14-1 1,2-bis<2-(3-phenylureido)benzoyl>hydrazine 
• 94775-13-0 1-(2-Hydrazinocarbonyl-phenyl)-3-phenyl-urea 
• 4248-15-1 2-anilinoquinazolin-4(3H)-one 
• 30386-01-7 3-amino-2,4(1H,3H)-quinazolinedione 
• 603-23-6 3-phenyl-2,4-(1H,3H)-quinazolinedione 

Relevant articles and documents

Microwave-assisted palladium-catalysed isonitrile insertion in 2-bromophenylureas for efficient synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines

A general route to the synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines via palladium-catalysed isonitrile insertion in 2-bromophenylureas succeeded by a C-O cross-coupling of the intermediate imidoylpalladium species under microwave irradiation is reported. This journal is

Mechanochemical Synthesis of Substituted 4H-3,1-Benzoxazin-4-ones, 2-Aminobenzoxazin-4-ones, and 2-Amino-4H-3,1-benzothiazin-4-ones Mediated by 2,4,6-Trichloro-1,3,5-triazine and Triphenylphosphine

A mild and convenient approach for the synthesis of 2-substituted 4H-3,1-benzoxazin-4-ones, 2-aminobenzoxazin-4-ones, and 2-amino-4H-3,1-benzothiazin-4-ones under solvent-assisted grinding is reported. In the presence of 2,4,6-trichloro-1,3,5-triazine and

A convenient palladium-catalyzed carbonylative synthesis of 2-aminbenzoxazinones from 2-bromoanilines and isocyanates

Mon ami(ne)! A general and convenient methodology for 2-aminobenzoxazinone synthesis has been developed (see scheme). Readily available 2-bromoanilines and isocyanates were used as substrates and various products have been prepared in good yields. Notably, [Mo(CO)6] as a solid CO source was applied instead of gas. Copyright