N-methyl-4-(N,N-dimethylamino)benzylidene amine N-oxide

Base Information

• Chemical Name: N-methyl-4-(N,N-dimethylamino)benzylidene amine N-oxide
• CAS No.: 203731-12-8
• Molecular Formula: C₁₀H₁₄N₂O
• Molecular Weight: 178.234
• Mol file: 203731-12-8.mol

Synonyms:

Chemical Property of N-methyl-4-(N,N-dimethylamino)benzylidene amine N-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methyl-4-(N,N-dimethylamino)benzylidene amine N-oxide

There total 9 articles about N-methyl-4-(N,N-dimethylamino)benzylidene amine N-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-methylhydroxyamine hydrochloride (4229-44-1) + 4-dimethylamino-benzaldehyde (100-10-7) → C--N-methylnitrone (203731-12-8,33184-68-8,16089-69-3)

Guidance literature:

With sodium sulfate; sodium carbonate; at 20 ℃; for 0.0833333h; Neat (no solvent);

DOI:10.3390/molecules16086677

Reference yield: 87.0%

N-methylhydroxyamine hydrochloride (4229-44-1) + 4-dimethylamino-benzaldehyde (100-10-7) → N-methyl,α-(4-dimethylamino)phenyl nitrone (203731-12-8,33184-68-8,16089-69-3)

Guidance literature:

With sodium hydrogencarbonate; magnesium sulfate; In dichloromethane; for 24h; Heating;

DOI:10.1021/jo00111a036

Reference yield:

C16H32N2O2Si2 → N-methyl,α-(4-dimethylamino)phenyl nitrone (203731-12-8,33184-68-8,16089-69-3)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In benzene; for 42h; Yield given; Ambient temperature;

DOI:10.1021/jo00350a110

upstream raw materials:

methylamine hydrochloride

4-dimethylamino-benzaldehyde

N-methylhydroxyamine hydrochloride

N-(4-dimethylamino-benzyl)-N-methyl-hydroxylamine

Downstream raw materials:

3-(4-dimethylamino-phenyl)-2,4,4-trimethyl-isoxazolidin-5-one

3t-(4-dimethylamino-phenyl)-2-methyl-5-oxo-isoxazolidine-4r-carboxylic acid methyl ester

4-(Dimethylamino)-N¹-methyl-N²-ethylbenzamidinyl-N¹-oxid

4-(Dimethylamino)-N¹,N²-dimethylbenzamidinyl-N¹-oxid