2-Propenoic acid, 2-(acetylamino)-3-phenyl-, phenylmethyl ester, (2Z)-

Base Information

Chemical Name:2-Propenoic acid, 2-(acetylamino)-3-phenyl-, phenylmethyl ester, (2Z)-
CAS No.:1407998-02-0
Molecular Formula:C₁₈H₁₇NO₃
Molecular Weight:295.338
Hs Code.:
DSSTox Substance ID:DTXSID601153234
ChEMBL ID:CHEMBL1582459

Synonyms:MLS001149299;CHEMBL1582459;DTXSID601153234;HMS2982H15;AKOS001438004;SMR000688158;Z16050592;2-Propenoic acid, 2-(acetylamino)-3-phenyl-, phenylmethyl ester, (2Z)-;1407998-02-0

Suppliers and Price of 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, phenylmethyl ester, (2Z)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, phenylmethyl ester, (2Z)-

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:295.12084340
Heavy Atom Count:22
Complexity:405

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NC(=CC1=CC=CC=C1)C(=O)OCC2=CC=CC=C2
Isomeric SMILES:CC(=O)N/C(=C\C1=CC=CC=C1)/C(=O)OCC2=CC=CC=C2

Technology Process of 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, phenylmethyl ester, (2Z)-

There total 3 articles about 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, phenylmethyl ester, (2Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55065-02-6,64590-80-3,5469-45-4
2-(N-acetylamino)cinnamic acid

: 100-39-0
benzyl bromide

: 1407998-02-0
(Z)-benzyl 2-acetamido-3-phenylacrylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1021/acs.orglett.0c02229

Reference yield:

: 100-52-7
benzaldehyde

: 1407998-02-0
(Z)-benzyl 2-acetamido-3-phenylacrylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium acetate; acetic anhydride / 13 h / 20 - 80 °C

1.2: 1 h / 20 °C

2.1: triethylamine / 3 h / Reflux

With sodium acetate; acetic anhydride; triethylamine;
DOI:10.1021/jo302073e