Pyrazolo(4,3-c)(1,2)benzothiazine-3-carboxamide, 1,4-dihydro-1-(p-chlorophenyl)-N-(3-(cyclohexylamino)propyl)-4-methyl-, 5,5-dioxide

Base Information

Chemical Name:Pyrazolo(4,3-c)(1,2)benzothiazine-3-carboxamide, 1,4-dihydro-1-(p-chlorophenyl)-N-(3-(cyclohexylamino)propyl)-4-methyl-, 5,5-dioxide
CAS No.:81761-98-0
Molecular Formula:C₂₆H₃₀ClN₅O₃S
Molecular Weight:528.075
Hs Code.:
DSSTox Substance ID:DTXSID90231346
Nikkaji Number:J66.463D
Wikidata:Q83112253
Mol file:81761-98-0.mol

Synonyms:81761-98-0;Pyrazolo(4,3-c)(1,2)benzothiazine-3-carboxamide, 1,4-dihydro-1-(p-chlorophenyl)-N-(3-(cyclohexylamino)propyl)-4-methyl-, 5,5-dioxide;C26H30ClN5O3S;DTXSID90231346;C26-H30-Cl-N5-O3-S;LS-128946;1-(p-Chlorophenyl)-3-[3-(cyclohexylamino)propylaminocarbonyl]-4-methyl-1,4-dihydropyrazolo[4,3-c][1,2]benzothiazine 5,5-dioxide

Suppliers and Price of Pyrazolo(4,3-c)(1,2)benzothiazine-3-carboxamide, 1,4-dihydro-1-(p-chlorophenyl)-N-(3-(cyclohexylamino)propyl)-4-methyl-, 5,5-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Pyrazolo(4,3-c)(1,2)benzothiazine-3-carboxamide, 1,4-dihydro-1-(p-chlorophenyl)-N-(3-(cyclohexylamino)propyl)-4-methyl-, 5,5-dioxide

Chemical Property:

PSA：108.20000
Density:1.42g/cm³
LogP:6.48490
XLogP3:4.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:527.1757887
Heavy Atom Count:36
Complexity:856

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C3=CC=CC=C3S1(=O)=O)N(N=C2C(=O)NCCCNC4CCCCC4)C5=CC=C(C=C5)Cl

Technology Process of Pyrazolo(4,3-c)(1,2)benzothiazine-3-carboxamide, 1,4-dihydro-1-(p-chlorophenyl)-N-(3-(cyclohexylamino)propyl)-4-methyl-, 5,5-dioxide

There total 4 articles about Pyrazolo(4,3-c)(1,2)benzothiazine-3-carboxamide, 1,4-dihydro-1-(p-chlorophenyl)-N-(3-(cyclohexylamino)propyl)-4-methyl-, 5,5-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 81761-78-6
1-(4-Chloro-phenyl)-4-methyl-5,5-dioxo-4,5-dihydro-1H-5λ⁶-thia-1,2,4-triaza-cyclopenta[a]naphthalene-3-carboxylic acid methyl ester

: 3312-60-5
N-(3-aminopropyl)cyclohexylamine

: 81761-98-0
1-(4-Chloro-phenyl)-4-methyl-5,5-dioxo-4,5-dihydro-1H-5λ⁶-thia-1,2,4-triaza-cyclopenta[a]naphthalene-3-carboxylic acid (3-cyclohexylamino-propyl)-amide

Guidance literature:: for 2h; Heating;

Reference yield:

: 5510-10-1
2-methyl-2H-1,2-benzothiazine-4-(3H)-one-1,1-dioxyde

: 81761-98-0
1-(4-Chloro-phenyl)-4-methyl-5,5-dioxo-4,5-dihydro-1H-5λ⁶-thia-1,2,4-triaza-cyclopenta[a]naphthalene-3-carboxylic acid (3-cyclohexylamino-propyl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 62.3 percent / sodium / benzene; methanol / 3 h / Ambient temperature

2: 78 percent / methanol / 5 h / Heating

3: 74 percent / 2 h / Heating

With sodium; In methanol; benzene;

Reference yield:

: 1073-69-4
N-4-chlorophenylhydrazine

: 81761-98-0
1-(4-Chloro-phenyl)-4-methyl-5,5-dioxo-4,5-dihydro-1H-5λ⁶-thia-1,2,4-triaza-cyclopenta[a]naphthalene-3-carboxylic acid (3-cyclohexylamino-propyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / methanol / 5 h / Heating

2: 74 percent / 2 h / Heating

In methanol;