6-Chloro-2,3-dihydrobenzofuran

Base Information

• Chemical Name: 6-Chloro-2,3-dihydrobenzofuran
• CAS No.: 289058-21-5
• Molecular Formula: C₈H₇ClO
• Molecular Weight: 154.596
• DSSTox Substance ID: DTXSID60573028
• Nikkaji Number: J1.330.905A
• Wikidata: Q82461589
• Mol file: 289058-21-5.mol

Synonyms:6-Chloro-2,3-dihydrobenzofuran;289058-21-5;6-CHLORO-2,3-DIHYDRO-BENZOFURAN;6-chloro-2,3-dihydro-1-benzofuran;Benzofuran, 6-chloro-2,3-dihydro-;dihydro-6-chlorobenzofuran;SCHEMBL1701850;DTXSID60573028;FVTNBEQDTWECHJ-UHFFFAOYSA-N;MFCD18914308;SB36400;BS-50116;CS-0128133;E84949

Chemical Property of 6-Chloro-2,3-dihydrobenzofuran

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 154.0185425
• Heavy Atom Count: 10
• Complexity: 126

Purity/Quality:

97% ^*data from raw suppliers

6-Chloro-2,3-dihydro-benzofuran 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COC2=C1C=CC(=C2)Cl

Technology Process of 6-Chloro-2,3-dihydrobenzofuran

There total 3 articles about 6-Chloro-2,3-dihydrobenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-dichlorophenylethyl alcohol (81156-68-5) → 2,4-dichlorotoluene (95-73-8) + 2,4-dichlorostyrene (2123-27-5) + 6-chloro-2,3-dihydrobenzofuran (289058-21-5)

Guidance literature:

2,4-dichlorophenylethyl alcohol; With sodium hydride; In pyridine; at 40 ℃; for 0.25h;

copper(l) chloride; In pyridine; for 4h; Heating;

DOI:10.1016/S0040-4039(00)00548-7

Reference yield:

2,4-dichlorophenylethyl alcohol (81156-68-5) → 2,4-dichlorotoluene (95-73-8) + 6-chloro-2,3-dihydrobenzofuran (289058-21-5)

Guidance literature:

2,4-dichlorophenylethyl alcohol; With sodium hydride; In toluene; at 40 ℃; for 0.25h;

copper(l) chloride; In ethyl acetate; toluene; for 24h; Heating;

DOI:10.1016/S0040-4039(00)00548-7

Reference yield:

→ 6-chloro-2,3-dihydrobenzofuran (289058-21-5)

Guidance literature:

upstream raw materials:

2,4-dichlorophenylethyl alcohol