95-73-8 Usage
Description
2,4-Dichlorotoluene is a clear colorless liquid with chemical properties that make it suitable for various applications across different industries.
Uses
Used in Chemical Synthesis:
2,4-Dichlorotoluene is used as an oxidant and a solvent for the anaerobic catalytic oxidation of secondary alcohols, utilizing an in situ (N-heterocyclic carbene)-Ni(0) system. This application takes advantage of its chemical properties to facilitate efficient and selective reactions.
Used in Microbial Culture Media:
In the field of microbiology, 2,4-Dichlorotoluene serves as a growth supplement in the culture media of Ralstonia sp. strain PS12. Its presence in the media helps support the growth and activity of the microorganism, which can be crucial for various biotechnological applications.
Used in Environmental Analysis:
2,4-Dichlorotoluene is employed in the development of a sensitive method for the analysis of chlorotoluenes in water samples. This method, based on solid-phase microextraction followed by gas chromatography-tandem mass spectrometry, allows for the accurate detection and quantification of chlorotoluenes, contributing to environmental monitoring and protection efforts.
Preparation
2,4-Dichlorotoluene is synthesized by diazotization and chlorination with 2,4-diaminotoluene as raw material. First, hydrochloric acid and water into the reaction pot, heated to 50°C, stirring under the dissolution of 2,4-diaminotoluene, then hydrochloric acid and cuprous chloride into the pot, the 1% sodium nitrite solution evenly added, the temperature is maintained at about 60°C, resting stratification, the lower layer of crude product washed with water to neutral, add alkali to alkaline, and then water to remove the alkali, divided 2,4-dichlorotoluene crude product, water distillation of finished products.
Synthesis Reference(s)
Tetrahedron Letters, 32, p. 2759, 1991 DOI: 10.1016/0040-4039(91)85078-J
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Simple aromatic halogenated organic compounds, such as 2,4-Dichlorotoluene, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Purification Methods
Recrystallise 2,4-dichlorotoluene from EtOH at low temperature or fractionally distil it. [Beilstein 5 IV 815.]
Check Digit Verification of cas no
The CAS Registry Mumber 95-73-8 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 95-73:
(4*9)+(3*5)+(2*7)+(1*3)=68
68 % 10 = 8
So 95-73-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H6Cl2/c1-5-2-3-6(8)4-7(5)9/h2-4H,1H3
95-73-8Relevant articles and documents
Production process of high-purity 2,4-dichlorotoluene
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Paragraph 0021-0032, (2019/07/04)
The invention relates to the technical field of compound synthesis and purification, and particularly relates to a production process of high-purity 2,4-dichlorotoluene. The method comprises the following steps: carrying out catalytic synthesis on 2,4-dichlorotoluene by using p-chlorotoluene and chlorine, carrying out alkali washing, recovering fractions by rectifying, and carrying out purifying crystallization to obtain the high-purity 2,4-dichlorotoluene. The method solves the problem that 2,4-dichlorotoluene is low in yield and purity and is not easy to purify in the prior art. The prepared2,4-dichlorotoluene has the advantages that the yield is high, purity is high and materials can be recycled.
H β molecular sieve catalytic O-chlorotoluene preparation 2, 6 - dichloro toluene method (by machine translation)
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Paragraph 0026; 0028-0031, (2017/08/26)
The invention relates to 2, 6 - dichloro toluene preparation technology field, in particular to a molecular sieve catalyst H β of O-toluene selective chlorination of preparation 2, 6 - dichloro toluene. The invention relates to a low cost of O-toluene as the raw materials, chlorine is the chlorinating agent, H β molecular sieve as the catalyst, adopt the one-step chlorination process, catalytic O-toluene selective chlorination of preparation 2, 6 - dichloro toluene, the process is easy to operate, simple steps, low production cost, easy industrialization. (by machine translation)
A chloro-toluene-ionic liquid catalyst preparation 2,6 the method of [...] dichloro-toluene
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Paragraph 0024; 0027; 0032, (2017/02/24)
The invention discloses a method for preparing 2,6-dichlorotoluene by catalyzing o-chlorotoluene with an ionic liquid. According to the method for preparing 2,6-dichlorotoluene, Cl2 is taken as a chlorinating agent, under the action of a catalyst, namely, an aluminium chlorate ionic liquid, a raw material, namely, o-chlorotoluene, is directionally chlorinated, and the 2,6-dichlorotoluene is prepared; an intermediate of the aluminium chlorate ionic liquid is [BMIM]Cl, the molar ratio of AlCl3 to [BMIM]Cl is 1:3, and the usage amount of the aluminium chlorate ionic liquid accounts for 0.1%-1% of the mass of o-chlorotoluene; the method for preparing 2,6-dichlorotoluene by selectively chlorinating the o-chlorotoluene is simple in technology and mild in reaction condition, the used aluminium chlorate ionic liquid is good in catalytic activity and good in stability, can be separated from a product easily and can significantly improve the selectivity of 2,6-dichlorotoluene, and the method has the very high industrial application value.
