1-(1-(2-Hydroxyethyl)-5-methyl-1H-pyrazol-4-yl)ethanone

Base Information Edit

Chemical Name:1-(1-(2-Hydroxyethyl)-5-methyl-1H-pyrazol-4-yl)ethanone
CAS No.:5078-59-1
Molecular Formula:C₈H₁₂N₂O₂
Molecular Weight:168.195
Hs Code.:
DSSTox Substance ID:DTXSID101204650
Mol file:5078-59-1.mol

Synonyms:5078-59-1;1-(1-(2-Hydroxyethyl)-5-methyl-1H-pyrazol-4-yl)ethanone;1-[1-(2-Hydroxyethyl)-5-methyl-1H-pyrazol-4-yl]ethanone;SCHEMBL13126455;DTXSID101204650;4-acetyl-1-(2-hydroxyethyl)-5-methyl-pyrazole

Suppliers and Price of 1-(1-(2-Hydroxyethyl)-5-methyl-1H-pyrazol-4-yl)ethanone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 1-(1-(2-Hydroxyethyl)-5-methyl-1H-pyrazol-4-yl)ethanone Edit

Chemical Property:

XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:168.089877630
Heavy Atom Count:12
Complexity:172

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=NN1CCO)C(=O)C

Technology Process of 1-(1-(2-Hydroxyethyl)-5-methyl-1H-pyrazol-4-yl)ethanone

There total 4 articles about 1-(1-(2-Hydroxyethyl)-5-methyl-1H-pyrazol-4-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 105224-04-2,948292-73-7
1-(3-methyl-1H-pyrazol-4-yl)ethanone

: 540-51-2
2-bromoethanol

: 5078-59-1
1-β-Hydroxyethyl-4-acetyl-5-methylpyrazol

: 1-[1-(2-Hydroxy-ethyl)-3-methyl-1H-pyrazol-4-yl]-ethanone

Guidance literature:: With sodium methylate; In methanol; at 40 ℃; for 18h;

Reference yield:

: 87150-12-7
ethyl 4-acetyl-3-methyl-1H-pyrazole-1-carboxylate

: 5078-59-1
1-β-Hydroxyethyl-4-acetyl-5-methylpyrazol

Guidance literature:: Multi-step reaction with 2 steps

1: 5.6 g / aq.KOH / ethanol / 8 h / Heating

2: 20 percent / MeONa / methanol / 18 h / 40 °C

With potassium hydroxide; sodium methylate; In methanol; ethanol;