(2S)-2-methyl-3-phenylpropanoic acid

Base Information

Chemical Name:(2S)-2-methyl-3-phenylpropanoic acid
CAS No.:14367-54-5
Molecular Formula:C₁₀H₁₂O₂
Molecular Weight:164.204
Hs Code.:
European Community (EC) Number:862-636-2
Nikkaji Number:J70.839I
Wikidata:Q27096892
Metabolomics Workbench ID:150840

Synonyms:(2S)-2-methyl-3-phenylpropanoic acid;14367-54-5;DEAMINO-METHYL-PHENYLALANINE;(s)-2-methyl-3-phenylpropanoic acid;(S)-2-Benzylpropanoic acid;SCHEMBL265135;MFCD20638188;(2S)-2-methyl-3-phenylpropanoicacid;AKOS034822810;DB07673;EN300-213851;Q27096892;Z1262510261

Suppliers and Price of (2S)-2-methyl-3-phenylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (2S)-2-methyl-3-phenylpropanoic acid

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:164.083729621
Heavy Atom Count:12
Complexity:148

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CC1=CC=CC=C1)C(=O)O
Isomeric SMILES:C[C@@H](CC1=CC=CC=C1)C(=O)O

Technology Process of (2S)-2-methyl-3-phenylpropanoic acid

There total 93 articles about (2S)-2-methyl-3-phenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 5669-19-2
2-Benzyl-2-propenoic acid

: 1009-67-2,5628-72-8,14367-54-5,14367-67-0
2-methyl-3-phenylpropionic acid

Guidance literature:: With C₄₈H₅₀Cl₄N₂O₂P₂Ru₃; hydrogen; sodium hydrogencarbonate; In methanol; at 20 ℃; for 24h; under 3750.38 Torr; enantioselective reaction; Autoclave;
DOI:10.1021/acs.orglett.6b00748

Reference yield: 97.0%

: 1895-97-2
2-methyl-3-phenylacrylic acid

: 1009-67-2,5628-72-8,14367-54-5,14367-67-0
2-methyl-3-phenylpropionic acid

Guidance literature:: With C₄₂H₄₈CoP₂; hydrogen; triethylamine; zinc; In methanol; at 50 ℃; for 16h; under 25858.1 Torr; Reagent/catalyst; Solvent; Temperature; enantioselective reaction;
DOI:10.1021/jacs.9b13876

Reference yield: 97.0%

: 904296-09-9
(2S,4R)-2-trifluoromethyl-3-[(S)-2-methyl-3-phenylpropanoyl]-4-phenyloxazolidine

: 1009-67-2,5628-72-8,14367-54-5,14367-67-0
2-methyl-3-phenylpropionic acid

: 203176-56-1
(2S,4R)-2-trifluoromethyl-4-phenyl-1,3-oxazolidine

Guidance literature:: (2S,4R)-2-trifluoromethyl-3-[(S)-2-methyl-3-phenylpropanoyl]-4-phenyloxazolidine; With lithium aluminium tetrahydride; In diethyl ether; at -10 ℃; for 0.5h;

With sodium chloride; In diethyl ether; at -10 - 20 ℃;

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 1.2h; Further stages.;
DOI:10.1002/anie.200600738