N⁶-(4-monomethoxytrityl)-9-<2-phosphonomethoxy>ethyl>adenine

Base Information

• Chemical Name: N⁶-(4-monomethoxytrityl)-9-<2-phosphonomethoxy>ethyl>adenine
• CAS No.: 1026243-39-9
• Molecular Formula: C₄₂H₅₂N₅O₇PS₂
• Molecular Weight: 834.01
• Mol file: 1026243-39-9.mol

Synonyms:

Chemical Property of N⁶-(4-monomethoxytrityl)-9-<2-phosphonomethoxy>ethyl>adenine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N⁶-(4-monomethoxytrityl)-9-<2-phosphonomethoxy>ethyl>adenine

There total 2 articles about N⁶-(4-monomethoxytrityl)-9-<2-phosphonomethoxy>ethyl>adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

N6-(4-monomethoxytrityl)-9-(2-phosphonomethoxyethyl)adenine (153235-86-0) + S-(2-hydroxyethyl) 2,2-dimethylpropanethioate (153121-88-1) → N6-(4-monomethoxytrityl)-9-<2-phosphonomethoxy>ethyl>adenine (1026243-39-9) + 2,2-Dimethyl-thiopropionic acid S-(2-{hydroxy-[2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-ethoxymethyl]-phosphinoyloxy}-ethyl) ester

Guidance literature:

With pyridine; 1-(mesitylene-2-sulfonyl)-3-nitro-1H-1,2,4-triazole; for 12h; Ambient temperature;

DOI:10.1021/jm960289o

Reference yield:

N6-(4-monomethoxytrityl)-9-(2-phosphonomethoxyethyl)adenine (153235-86-0) + S-(2-hydroxyethyl) 2,2-dimethylpropanethioate (153121-88-1) → N6-(4-monomethoxytrityl)-9-<2-phosphonomethoxy>ethyl>adenine (1026243-39-9)

Guidance literature:

With MSNT; In pyridine;

DOI:10.1080/15257779508012428

upstream raw materials:

N⁶-(4-monomethoxytrityl)-9-(2-phosphonomethoxyethyl)adenine

S-(2-hydroxyethyl) 2,2-dimethylpropanethioate