4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid

Base Information

Chemical Name:4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid
CAS No.:124688-44-4
Molecular Formula:C₁₄H₁₄FNO₆
Molecular Weight:311.267
Hs Code.:

Synonyms:

Suppliers and Price of 4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid

There total 2 articles about 4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 124688-42-2,124688-43-3
N-benzyloxycarbonyl-4-(R/S)-fluoro-D/L-glutamic acid

: 124688-44-4,124688-45-5
4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 7h; Heating;
DOI:10.1021/jm00165a021

Reference yield:

: 2708-77-2,149117-03-3,91383-48-1,91383-47-0
D,L-erythro,threo-4-fluoroglutamic acid

: 124688-44-4,124688-45-5
4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / NaHCO₃ / H₂O / 5 h

2: 65 percent / TsOH / benzene / 7 h / Heating

With sodium hydrogencarbonate; toluene-4-sulfonic acid; In water; benzene;
DOI:10.1021/jm00165a021

Reference yield: 50.0%

: 16874-06-9
di-tert-butyl L-glutamate

: 124688-44-4,124688-45-5
4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionic acid

: 124688-46-6,124815-52-7,124815-53-8,124815-54-9
N-<4-(N-Cbz-D,L-erythro,threo-5-oxo-4-oxazolidinyl)-2-fluoropropionyl>-L-glutamic acid di-tert-butyl ester

Guidance literature:: With benzotriazol-1-ol; 2`,3`-dideoxycytidine; In dichloromethane; for 72h; Ambient temperature;
DOI:10.1021/jm00165a021