Technology Process of C30H34O7
There total 5 articles about C30H34O7 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
dibenzyl (E)-2-(4-oxobut-2-enyl)-2-((tetrahydrofuran-2-yl)methyl)malonate;
With
silver hexafluoroantimonate; (2R,5R)-5-benzyl-2-tert-butyl-3-methyl-imidazolidin-4-one hydrochloride;
In
chloroform;
at 20 ℃;
Inert atmosphere;
ethyl (triphenylphosphoranylidene)acetate;
In
chloroform;
at 30 ℃;
for 96h;
optical yield given as %ee;
enantioselective reaction;
Inert atmosphere;
DOI:10.1002/anie.201204274
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / methanol / 1 h
2.1: Dess-Martin periodane / dichloromethane / 20 °C / Inert atmosphere
3.1: silver hexafluoroantimonate; (2R,5R)-5-benzyl-2-tert-butyl-3-methyl-imidazolidin-4-one hydrochloride / chloroform / 20 °C / Inert atmosphere
3.2: 96 h / 30 °C / Inert atmosphere
With
silver hexafluoroantimonate; (2R,5R)-5-benzyl-2-tert-butyl-3-methyl-imidazolidin-4-one hydrochloride; potassium carbonate; Dess-Martin periodane;
In
methanol; dichloromethane; chloroform;
3.1: Prins reaction / 3.2: Wittig reaction;
DOI:10.1002/anie.201204274
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / N,N-dimethyl-formamide; toluene / 0.5 h / 20 °C / Inert atmosphere
1.2: 0.5 h / Inert atmosphere
2.1: potassium carbonate / methanol / 1 h
3.1: Dess-Martin periodane / dichloromethane / 20 °C / Inert atmosphere
4.1: silver hexafluoroantimonate; (2R,5R)-5-benzyl-2-tert-butyl-3-methyl-imidazolidin-4-one hydrochloride / chloroform / 20 °C / Inert atmosphere
4.2: 96 h / 30 °C / Inert atmosphere
With
silver hexafluoroantimonate; (2R,5R)-5-benzyl-2-tert-butyl-3-methyl-imidazolidin-4-one hydrochloride; sodium hydride; potassium carbonate; Dess-Martin periodane;
In
methanol; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene;
4.1: Prins reaction / 4.2: Wittig reaction;
DOI:10.1002/anie.201204274
