C₅₁H₈₈ClN₇O₁₀

Base Information

• Chemical Name: C₅₁H₈₈ClN₇O₁₀
• CAS No.: 1609955-65-8
• Molecular Formula: C₅₁H₈₈ClN₇O₁₀
• Molecular Weight: 994.754
• Mol file: 1609955-65-8.mol

Synonyms:

Chemical Property of C₅₁H₈₈ClN₇O₁₀

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₁H₈₈ClN₇O₁₀

There total 4 articles about C₅₁H₈₈ClN₇O₁₀ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C26H44ClN3O3 + 2-(4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid (247193-74-4) → C51H88ClN7O10 (1609955-65-8)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1039/c4ob00384e

Reference yield:

Boc-(S)-Lys(2-Cl-Z)-OH (54613-99-9) → C51H88ClN7O10 (1609955-65-8)

Guidance literature:

Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 6 h / 0 °C

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;

DOI:10.1039/c4ob00384e

Reference yield:

n-Dodecylamine (124-22-1) → C51H88ClN7O10 (1609955-65-8)

Guidance literature:

Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 6 h / 0 °C

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;

DOI:10.1039/c4ob00384e

upstream raw materials:

2-(4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid

Boc-(S)-Lys(2-Cl-Z)-OH

n-Dodecylamine

C₃₁H₅₂ClN₃O₅