1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid

Base Information

Chemical Name:1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid
CAS No.:1232365-40-0
Molecular Formula:C₈H₁₀F₂O₄
Molecular Weight:208.162
Hs Code.:

Synonyms:

Suppliers and Price of 1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of 1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid

There total 5 articles about 1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 827032-79-1
diethyl 3,3-difluorocyclobutane-1,1-dicarboxylate

: 1232365-40-0
1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid

Guidance literature:: diethyl 3,3-difluorocyclobutane-1,1-dicarboxylate; With water; potassium hydroxide; In ethanol; at 20 ℃; Cooling with ice;

With hydrogenchloride; In water;

Reference yield:

: 54166-15-3
diethyl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate

: 1232365-40-0
1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen / palladium 10% on activated carbon / ethanol / 3.5 h / 20 °C / 2585.81 Torr

2: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C

3: diethylamino-sulfur trifluoride / dichloromethane / 20 °C

4: potassium hydroxide; water / ethanol / 20 °C / Cooling with ice

With diethylamino-sulfur trifluoride; water; hydrogen; pyridinium chlorochromate; potassium hydroxide; palladium 10% on activated carbon; In ethanol; dichloromethane;

Reference yield:

: 99974-66-0
diethyl 3-hydroxycyclobutane-1,1-dicarboxylate

: 1232365-40-0
1-(ethoxycarbonyl)-3,3-difluorocyclobutanecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C

2: diethylamino-sulfur trifluoride / dichloromethane / 20 °C

3: potassium hydroxide; water / ethanol / 20 °C

With diethylamino-sulfur trifluoride; water; pyridinium chlorochromate; potassium hydroxide; In ethanol; dichloromethane;