Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate

Base Information

Chemical Name:Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate
CAS No.:99974-66-0
Molecular Formula:C10H16O5
Molecular Weight:216.234
Hs Code.:2918199090
DSSTox Substance ID:DTXSID50563392
Wikidata:Q82447823
Mol file:99974-66-0.mol

Synonyms:Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate;99974-66-0;MFCD11878435;Diethyl3-hydroxycyclobutane-1,1-dicarboxylate;SCHEMBL1962459;3-hydroxycyclobutane-1,1-dicarboxylic acid diethyl ester;DTXSID50563392;HCVGFHCQRXXAGH-UHFFFAOYSA-N;AKOS015150335;DS-13138;SY033766;CS-0139607;diethyl 3-hydroxy-1,1-cyclobutanedicarboxylate;A858401;3-Hydroxy-cyclobutane-1,1-dicarboxylic acid diethyl ester;1,1-Cyclobutanedicarboxylic acid, 3-hydroxy-, 1,1-diethyl ester

Suppliers and Price of Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
Diethyl3-hydroxycyclobutane-1,1-dicarboxylate 95+%
250mg
$ 120.00

Crysdot
Diethyl3-hydroxycyclobutane-1,1-dicarboxylate 95%
10g
$ 970.00

Crysdot
Diethyl3-hydroxycyclobutane-1,1-dicarboxylate 95%
5g
$ 584.00

Chemenu
diethyl3-hydroxycyclobutane-1,1-dicarboxylate 95%
5g
$ 552.00

Chemenu
diethyl3-hydroxycyclobutane-1,1-dicarboxylate 95%
10g
$ 916.00

Chemenu
diethyl3-hydroxycyclobutane-1,1-dicarboxylate 95%
1g
$ 199.00

Biosynth Carbosynth
Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate
500 mg
$ 190.00

Biosynth Carbosynth
Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate
100 mg
$ 55.00

Biosynth Carbosynth
Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate
1 g
$ 331.25

Biosynth Carbosynth
Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate
2 g
$ 563.00

Total 22 raw suppliers

Chemical Property of Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Boiling Point:272.939oC at 760 mmHg
PKA:14.23±0.40(Predicted)
Flash Point:97.585oC
PSA：72.83000
Density:1.238g/cm3
LogP:0.25370
Storage Temp.:2-8°C
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:216.09977361
Heavy Atom Count:15
Complexity:235

Purity/Quality:

97% ^*data from raw suppliers

Diethyl3-hydroxycyclobutane-1,1-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1(CC(C1)O)C(=O)OCC

Technology Process of Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate

There total 2 articles about Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 54166-15-3
diethyl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate

: 99974-66-0
diethyl 3-hydroxycyclobutane-1,1-dicarboxylate

Guidance literature:: With hydrogen; palladium(II) hydroxide; In ethanol; water; at 20 ℃; for 8h;
DOI:10.1016/j.bmcl.2020.127527

Reference yield:

: 105-53-3
diethyl malonate

: 99974-66-0
diethyl 3-hydroxycyclobutane-1,1-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium ethylate; benzene / 170 °C

2: palladium; ethanol / Hydrogenation

With ethanol; sodium ethanolate; palladium; benzene;