Technology Process of 3-(cyclohexylamino)-7-fluorobenzo[e][1,2,4]triazine-1,4-dioxide
There total 6 articles about 3-(cyclohexylamino)-7-fluorobenzo[e][1,2,4]triazine-1,4-dioxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dihydrogen peroxide; trifluoroacetic anhydride;
In
tetrahydrofuran;
at 20 ℃;
DOI:10.1021/jm300123s
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: hydrogenchloride / water / Reflux
2.1: diethyl ether / 1 h / 100 °C
2.2: 3 h / 50 - 110 °C
2.3: 3 h / 50 - 110 °C
3.1: hydrogenchloride; trifluoroacetic acid; sodium nitrite / water / 1 h / 20 °C
4.1: trichlorophosphate / 3 h / Reflux
5.1: triethylamine / dichloromethane / 20 °C
6.1: dihydrogen peroxide; trifluoroacetic anhydride / tetrahydrofuran / 20 °C
With
hydrogenchloride; dihydrogen peroxide; triethylamine; trifluoroacetic acid; trifluoroacetic anhydride; sodium nitrite; trichlorophosphate;
In
tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1021/jm300123s
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: nitric acid; acetic anhydride / dichloromethane
2.1: hydrogenchloride / water / Reflux
3.1: diethyl ether / 1 h / 100 °C
3.2: 3 h / 50 - 110 °C
3.3: 3 h / 50 - 110 °C
4.1: hydrogenchloride; trifluoroacetic acid; sodium nitrite / water / 1 h / 20 °C
5.1: trichlorophosphate / 3 h / Reflux
6.1: triethylamine / dichloromethane / 20 °C
7.1: dihydrogen peroxide; trifluoroacetic anhydride / tetrahydrofuran / 20 °C
With
hydrogenchloride; dihydrogen peroxide; nitric acid; acetic anhydride; triethylamine; trifluoroacetic acid; trifluoroacetic anhydride; sodium nitrite; trichlorophosphate;
In
tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1021/jm300123s
