Technology Process of (3aR,4R,6aS)-2,2-Dimethyl-4-phenyl-5-(toluene-4-sulfonyl)-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole
There total 6 articles about (3aR,4R,6aS)-2,2-Dimethyl-4-phenyl-5-(toluene-4-sulfonyl)-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: KHMDS
2: 60 percent / K2CO3 / dimethylformamide
3: 85 percent / Grubbs II
4: 81 percent / K3Fe(CN)6 / OsO4
5: 79 percent / TsOH
With
potassium hexamethylsilazane; potassium carbonate; toluene-4-sulfonic acid; potassium hexacyanoferrate(III);
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; osmium(VIII) oxide;
In
N,N-dimethyl-formamide;
1: Wittig reaction;
DOI:10.1016/j.tetlet.2006.02.092
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1,3-dibromo-5,5-dimethylhydantoin
2: KHMDS
3: 60 percent / K2CO3 / dimethylformamide
4: 85 percent / Grubbs II
5: 81 percent / K3Fe(CN)6 / OsO4
6: 79 percent / TsOH
With
1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; potassium hexamethylsilazane; potassium carbonate; toluene-4-sulfonic acid; potassium hexacyanoferrate(III);
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; osmium(VIII) oxide;
In
N,N-dimethyl-formamide;
2: Wittig reaction;
DOI:10.1016/j.tetlet.2006.02.092
