Ethanone,1-[5-(2-fluorophenyl)-4,5-dihydro-3-[2-[(1H-indol-3-ylmethylene)amino]phenyl]-1H-pyrazol-1-yl]-

Base Information

Chemical Name:Ethanone,1-[5-(2-fluorophenyl)-4,5-dihydro-3-[2-[(1H-indol-3-ylmethylene)amino]phenyl]-1H-pyrazol-1-yl]-
CAS No.:93415-41-9
Molecular Formula:C₂₆H₂₁FN₄O
Molecular Weight:424.477
Hs Code.:

Synonyms:1H-Pyrazole,1-acetyl-5-(2-fluorophenyl)-4,5-dihydro-3-[2-[(1H-indol-3-ylmethylene)amino]phenyl]-(9CI)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethanone,1-[5-(2-fluorophenyl)-4,5-dihydro-3-[2-[(1H-indol-3-ylmethylene)amino]phenyl]-1H-pyrazol-1-yl]-

Chemical Property:

Purity/Quality:

Safty Information:

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Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethanone,1-[5-(2-fluorophenyl)-4,5-dihydro-3-[2-[(1H-indol-3-ylmethylene)amino]phenyl]-1H-pyrazol-1-yl]-

There total 4 articles about Ethanone,1-[5-(2-fluorophenyl)-4,5-dihydro-3-[2-[(1H-indol-3-ylmethylene)amino]phenyl]-1H-pyrazol-1-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 89410-23-1
2-fluoro-2'-(indol-3-yl-methyleneamino)chalkone

: 64-19-7,77671-22-8
acetic acid

: 93415-41-9
1-[5-(2-Fluoro-phenyl)-3-(2-{[1-(1H-indol-3-yl)-meth-(E)-ylidene]-amino}-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone

Guidance literature:: With hydrazine hydrate; In ethanol; Heating;

Reference yield:

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 93415-41-9
1-[5-(2-Fluoro-phenyl)-3-(2-{[1-(1H-indol-3-yl)-meth-(E)-ylidene]-amino}-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / methanol / 18 h / Heating

2: 65 percent / piperidine / ethanol / 10 h / Heating

3: 50 percent / H₂N-NH₂*H₂O / ethanol / Heating

With piperidine; hydrazine hydrate; In methanol; ethanol;

Reference yield:

: 551-93-9
2-aminoacetophenone

: 93415-41-9
1-[5-(2-Fluoro-phenyl)-3-(2-{[1-(1H-indol-3-yl)-meth-(E)-ylidene]-amino}-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / methanol / 18 h / Heating

2: 65 percent / piperidine / ethanol / 10 h / Heating

3: 50 percent / H₂N-NH₂*H₂O / ethanol / Heating

With piperidine; hydrazine hydrate; In methanol; ethanol;