(+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine oxalate

Base Information

• Chemical Name: (+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine oxalate
• CAS No.: 1224246-43-8
• Molecular Formula: C₂H₂O₄*C₁₃H₁₇Cl₂NO₂
• Molecular Weight: 380.225
• Mol file: 1224246-43-8.mol

Synonyms:

Chemical Property of (+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine oxalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine oxalate

There total 3 articles about (+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2-hydroxypropyl)morpholine (2109-66-2) → (+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine oxalate (1224246-43-8)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / benzene / 20 h / 20 °C / Reflux

2: sodium hydroxide / water / 2 h / Reflux

3: diethyl ether

With thionyl chloride; sodium hydroxide; In diethyl ether; water; benzene;

DOI:10.1007/s00044-010-9316-3

Reference yield:

4-(2-chloropropyl)morpholine hydrochloride (100859-99-2) → (+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine oxalate (1224246-43-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water / 2 h / Reflux

2: diethyl ether

With sodium hydroxide; In diethyl ether; water;

DOI:10.1007/s00044-010-9316-3

Reference yield:

(+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine (1224246-42-7) + oxalic acid (144-62-7,97993-78-7) → (+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine oxalate (1224246-43-8)

Guidance literature:

In diethyl ether;

DOI:10.1007/s00044-010-9316-3

upstream raw materials:

(+/-)-4-[2-(2,4-dichlorophenoxy)propyl]morpholine

oxalic acid

4-(2-hydroxypropyl)morpholine

4-(2-chloropropyl)morpholine hydrochloride