Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester

Base Information

Chemical Name:Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester
CAS No.:77513-77-0
Molecular Formula:C₂₉H₄₇O₈P
Molecular Weight:554.661
Hs Code.:

Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester

Synonyms:

Suppliers and Price of Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester

There total 8 articles about Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 77513-77-0
Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / TsOH / diethyl ether

2: 70 percent / MCPBA , NaOAc / CH₂Cl₂ / Heating

3: 1.) LDA 2.) TMEDA / 1.) THF , -78 deg C 2.) HMPA

With N,N,N,N,-tetramethylethylenediamine; sodium acetate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; In diethyl ether; dichloromethane;
DOI:10.1016/S0040-4039(01)81818-9

Reference yield:

: 77514-08-0
(6R,7S)-7-Benzyloxy-6-methyl-6-(4-methyl-pent-4-enyl)-1,4-dioxa-spiro[4.5]decane

: 77513-77-0
Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) 9-BBN 2.) 30percent H₂O₂, 3N NaOH / 1.) THF

2: 99 percent / acetone , 2E-3N H₂SO₄

3: 90 percent / TsOH / diethyl ether

4: 70 percent / MCPBA , NaOAc / CH₂Cl₂ / Heating

5: 1.) LDA 2.) TMEDA / 1.) THF , -78 deg C 2.) HMPA

With sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; N,N,N,N,-tetramethylethylenediamine; sulfuric acid; dihydrogen peroxide; sodium acetate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; acetone; lithium diisopropyl amide; In diethyl ether; dichloromethane;
DOI:10.1016/S0040-4039(01)81818-9

Reference yield:

: 77514-07-9
5-((6R,7S)-7-Benzyloxy-6-methyl-1,4-dioxa-spiro[4.5]dec-6-yl)-pentan-2-one

: 77513-77-0
Phosphoric acid (6R,7S)-6-benzyloxy-7-methyl-7-[4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl]-4,5,6,7-tetrahydro-oxepin-2-yl ester diethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) NaH / 1.) DMSO

2: 1.) 9-BBN 2.) 30percent H₂O₂, 3N NaOH / 1.) THF

3: 99 percent / acetone , 2E-3N H₂SO₄

4: 90 percent / TsOH / diethyl ether

5: 70 percent / MCPBA , NaOAc / CH₂Cl₂ / Heating

6: 1.) LDA 2.) TMEDA / 1.) THF , -78 deg C 2.) HMPA

With sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; N,N,N,N,-tetramethylethylenediamine; sulfuric acid; dihydrogen peroxide; sodium acetate; sodium hydride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; acetone; lithium diisopropyl amide; In diethyl ether; dichloromethane;
DOI:10.1016/S0040-4039(01)81818-9