(E)-(1,2-dichlorovinyloxy)-2-deuteriobenzene

Base Information

• Chemical Name: (E)-(1,2-dichlorovinyloxy)-2-deuteriobenzene
• CAS No.: 1257326-15-0
• Molecular Formula: C₈H₆Cl₂O
• Molecular Weight: 190.033
• Mol file: 1257326-15-0.mol

Synonyms:

Chemical Property of (E)-(1,2-dichlorovinyloxy)-2-deuteriobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-(1,2-dichlorovinyloxy)-2-deuteriobenzene

There total 1 articles about (E)-(1,2-dichlorovinyloxy)-2-deuteriobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Trichloroethylene (79-01-6) + <2-D>-phenol (23951-01-1) → (E)-(1,2-dichlorovinyloxy)-2-deuteriobenzene (1257326-15-0)

Guidance literature:

<2-D>-phenol; With potassium hydride; In tetrahydrofuran; Inert atmosphere;

Trichloroethylene; In tetrahydrofuran; at -50 - 20 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201000787

Reference yield:

α,β-dichlorovinyl phenyl ether (60785-20-8) + (E)-(1,2-dichlorovinyloxy)-2-deuteriobenzene (1257326-15-0) + 4-methoxyphenylboronic acid (5720-07-0) → 2-(p-methoxyphenyl)-benzo[b]furan (19234-04-9) + 2-(4-methoxyphenyl)-7-deuteriobenzo[b]furan (1257326-13-8)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; cesium fluoride; bis[2-(diphenylphosphino)phenyl] ether; In 1,4-dioxane; at 100 ℃; for 12h; Mechanism; Inert atmosphere;

DOI:10.1002/ejoc.201000787

Reference yield:

α,β-dichlorovinyl phenyl ether (60785-20-8) + (E)-(1,2-dichlorovinyloxy)-2-deuteriobenzene (1257326-15-0) + 9-(3-phenylpropyl)-9-borabicyclo[3.3.1]nonane (180286-97-9) → 2-(3-phenylpropyl)benzo[b]furan (1034519-10-2) + 2-(3-phenylpropyl)-7-deuteriobenzo[b]furan (1257326-25-2)

Guidance literature:

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; caesium carbonate; In toluene; for 12h; Mechanism; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.201000787

upstream raw materials:

Trichloroethylene

<2-D>-phenol

Downstream raw materials:

2-(trans-2-phenylethenyl)benzo[b]furan

2-(trans-2-phenylethenyl)-7-deuteriobenzo[b]furan

2-(4-fluorophenyl)benzofuran

2-(4-fluorophenyl)-7-deuteriobenzo[b]furan