Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester

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Chemical Name:Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester
CAS No.:448963-41-5
Molecular Formula:C₄₄H₄₅N₇O₁₁S
Molecular Weight:879.948
Hs Code.:

Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester

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Chemical Property of Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester

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Technology Process of Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester

There total 5 articles about Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3397-32-8
N-(benzyloxycarbonyl)-phenylalanine-N-hydroxysuccinimide ester

: 448963-41-5
Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: NaHCO₃ / 1,2-dimethoxy-ethane; H₂O / Ambient temperature

2: 2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline / tetrahydrofuran / Ambient temperature

3: pyridine / CH₂Cl₂ / Ambient temperature

With pyridine; sodium hydrogencarbonate; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; water;

Reference yield:

: 623-04-1
4-aminobenzenemethanol

: 448963-41-5
Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline / tetrahydrofuran / Ambient temperature

2: pyridine / CH₂Cl₂ / Ambient temperature

With pyridine; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1161-13-3
N-Cbz-L-Phe

: 448963-41-5
Carbonic acid 4-[(S)-5-({amino-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-2-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-pentanoylamino]-benzyl ester 4-nitro-phenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: DCC / 0 - 20 °C

2: NaHCO₃ / 1,2-dimethoxy-ethane; H₂O / Ambient temperature

3: 2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline / tetrahydrofuran / Ambient temperature

4: pyridine / CH₂Cl₂ / Ambient temperature

With pyridine; sodium hydrogencarbonate; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; water;