N-methylfuran-2-carboximidoyl chloride

Base Information

• Chemical Name: N-methylfuran-2-carboximidoyl chloride
• CAS No.: 6521-33-1
• Molecular Formula: C₆H₆ClNO
• Molecular Weight: 143.573
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID90427883
• Mol file: 6521-33-1.mol

Synonyms:6521-33-1;N-methylfuran-2-carboximidoyl chloride;N-METHYLFURAN-2-CARBOXIMIDOYLCHLORIDE;N-methylfuran-2-carbonimidoyl chloride;DTXSID90427883;HMS1741N04;2-Furancarboximidoylchloride,N-methyl-;AKOS026727102;AKOS033005229;N-Methyl-furan-2-carboximidoyl chloride;(E)-N-methylfuran-2-carbonimidoyl chloride;EN300-14636;J-523679;Z104378178

Chemical Property of N-methylfuran-2-carboximidoyl chloride

Chemical Property:

• Vapor Pressure: 0.82mmHg at 25°C
• Boiling Point: 188.6°C at 760 mmHg
• Flash Point: 67.9°C
• PSA: 25.50000
• Density: 1.19g/cm³
• LogP: 1.89480
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 143.0137915
• Heavy Atom Count: 9
• Complexity: 124

Purity/Quality:

99% ^*data from raw suppliers

N-methylfuran-2-carbonimidoylchloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN=C(C1=CC=CO1)Cl

Technology Process of N-methylfuran-2-carboximidoyl chloride

There total 3 articles about N-methylfuran-2-carboximidoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

N-methylfuran-2-carboxamide (21402-85-7) → N-methylfuran-2-carboximidoyl chloride (6521-33-1)

Guidance literature:

With thionyl chloride; for 12h; Heating;

DOI:10.1016/S0040-4020(01)86710-7

Reference yield:

2-furanoic acid (88-14-2) → N-methylfuran-2-carboximidoyl chloride (6521-33-1)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂ / 5 h / Heating

2: 73 percent / 10 percent NaOH / H₂O / 12 h

3: 79 percent / SOCl₂ / 12 h / Heating

With sodium hydroxide; thionyl chloride; In water;

DOI:10.1016/S0040-4020(01)86710-7

Reference yield:

2-furancarbonyl chloride (527-69-5) → N-methylfuran-2-carboximidoyl chloride (6521-33-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / 10 percent NaOH / H₂O / 12 h

2: 79 percent / SOCl₂ / 12 h / Heating

With sodium hydroxide; thionyl chloride; In water;

DOI:10.1016/S0040-4020(01)86710-7

upstream raw materials:

N-methylfuran-2-carboxamide

2-furancarbonyl chloride

2-furanoic acid