N-(2-(1H-indol-3-yl)ethyl)-3-propionamidobenzamide

Base Information

Chemical Name:N-(2-(1H-indol-3-yl)ethyl)-3-propionamidobenzamide
CAS No.:1386665-72-0
Molecular Formula:C₂₀H₂₁N₃O₂
Molecular Weight:335.406
Hs Code.:

Synonyms:

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Chemical Property of N-(2-(1H-indol-3-yl)ethyl)-3-propionamidobenzamide

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Technology Process of N-(2-(1H-indol-3-yl)ethyl)-3-propionamidobenzamide

There total 3 articles about N-(2-(1H-indol-3-yl)ethyl)-3-propionamidobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.8%

: 79-03-8
propionyl chloride

: 33284-01-4
N-(2-(1H-indol-3-yl)ethyl)-3-aminobenzamide

: 1386665-72-0
N-(2-(1H-indol-3-yl)ethyl)-3-propionamidobenzamide

Guidance literature:: In dichloromethane; at 20 ℃; for 4h;
DOI:10.1021/ml500131a

Reference yield:

: 61-54-1
tryptamine

: 1386665-72-0
N-(2-(1H-indol-3-yl)ethyl)-3-propionamidobenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C

2: dichloromethane / 4 h / 20 °C

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ml500131a

Reference yield:

: 99-05-8,159139-79-4
meta-aminobenzoic acid

: 1386665-72-0
N-(2-(1H-indol-3-yl)ethyl)-3-propionamidobenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C

2: dichloromethane / 4 h / 20 °C

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ml500131a