(5S,6S,10R)-10-(2,4-dichlorophenyl)-14-[(E)-1-(2,4-dichlorophenyl)methylidene]-3,9-di(4-isopropylphenyl)-12-(1-phenylethyl)-1,4,7-trioxa-2,8,12-triazadispiro[4.0.4.4]tetradeca-2,8-diene

Base Information

• Chemical Name: (5S,6S,10R)-10-(2,4-dichlorophenyl)-14-[(E)-1-(2,4-dichlorophenyl)methylidene]-3,9-di(4-isopropylphenyl)-12-(1-phenylethyl)-1,4,7-trioxa-2,8,12-triazadispiro[4.0.4.4]tetradeca-2,8-diene
• CAS No.: 1245653-76-2
• Molecular Formula: C₄₇H₄₃Cl₄N₃O₃
• Molecular Weight: 839.689
• Mol file: 1245653-76-2.mol

Synonyms:

Chemical Property of (5S,6S,10R)-10-(2,4-dichlorophenyl)-14-[(E)-1-(2,4-dichlorophenyl)methylidene]-3,9-di(4-isopropylphenyl)-12-(1-phenylethyl)-1,4,7-trioxa-2,8,12-triazadispiro[4.0.4.4]tetradeca-2,8-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (5S,6S,10R)-10-(2,4-dichlorophenyl)-14-[(E)-1-(2,4-dichlorophenyl)methylidene]-3,9-di(4-isopropylphenyl)-12-(1-phenylethyl)-1,4,7-trioxa-2,8,12-triazadispiro[4.0.4.4]tetradeca-2,8-diene

There total 1 articles about (5S,6S,10R)-10-(2,4-dichlorophenyl)-14-[(E)-1-(2,4-dichlorophenyl)methylidene]-3,9-di(4-isopropylphenyl)-12-(1-phenylethyl)-1,4,7-trioxa-2,8,12-triazadispiro[4.0.4.4]tetradeca-2,8-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

3,5-bis[(E)-(2,4-dichlorophenyl)methylidene]-1-[(R)-1-phenylethyl]tetrahydro-4(1H)-pyridinone (1108205-34-0) + 4-isopropylphenylhydroximoyl chloride (61946-90-5) → (5R,6R,10S)-10-(2,4-dichlorophenyl)-14-[(E)-1-(2,4-dichlorophenyl)methylidene]-3,9-di(4-isopropylphenyl)-12-(1-phenylethyl)-1,4,7-trioxa-2,8,12-triazadispiro[4.0.4.4]tetradeca-2,8-diene (1245653-93-3) + (5S,6S,10R)-10-(2,4-dichlorophenyl)-14-[(E)-1-(2,4-dichlorophenyl)methylidene]-3,9-di(4-isopropylphenyl)-12-(1-phenylethyl)-1,4,7-trioxa-2,8,12-triazadispiro[4.0.4.4]tetradeca-2,8-diene (1245653-76-2) + (4R,5S,6R,11R,15S)-4,15-bis(2,4-dichlorophenyl)-3,9,14-tri(4-isopropyl-phenyl)-17-(1-phenylethyl)-1,7,10,12-tetraoxa-2,8,13,17-tetraazatrispiro[4.0.4.0.4.3]-octadeca-2,8,13-triene (1245654-03-8)

Guidance literature:

With triethylamine; In benzene; at 20 ℃; diastereoselective reaction;

DOI:10.1016/j.tetasy.2010.03.054

upstream raw materials:

3,5-bis[(E)-(2,4-dichlorophenyl)methylidene]-1-[(R)-1-phenylethyl]tetrahydro-4(1H)-pyridinone

4-isopropylphenylhydroximoyl chloride