dipalmitoyl PtdIns₄P

Base Information

• Chemical Name: dipalmitoyl PtdIns₄P
• CAS No.: 127996-98-9
• Molecular Formula: C₄₁H₈₀O₁₆P₂*3H₃N
• Molecular Weight: 942.116
• Mol file: 127996-98-9.mol

Synonyms:

Chemical Property of dipalmitoyl PtdIns₄P

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dipalmitoyl PtdIns₄P

There total 15 articles about dipalmitoyl PtdIns₄P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

C66H104O16P2 → dipalmitoyl PtdIns4P (127996-98-9)

Guidance literature:

C₆₆H₁₀₄O₁₆P₂; With trimethylsilyl bromide; In toluene; at 20 ℃; for 12h;

With methanol; at 0 ℃; for 1h;

DOI:10.1039/d0sc06219g

Reference yield:

4,6-di-O-benzyl-myo-inositol (149713-85-9,1214834-30-6) → dipalmitoyl PtdIns4P (127996-98-9)

Guidance literature:

Multi-step reaction with 12 steps

1.1: Thermomyces lanuginosus lipase / hexane / 15 h / 45 °C / Enzymatic reaction

2.1: toluene-4-sulfonic acid / dichloromethane / 18 h / 20 °C

3.1: palladium on activated charcoal; hydrogen / ethyl acetate / 2 h / 20 °C

4.1: 2,6-dimethylpyridine / tetrahydrofuran / -78 °C

5.1: toluene-4-sulfonic acid / dichloromethane / 18 h / 30 °C

6.1: tris(dimethylamino)sulfonium trimethylsilyldifluoride / N,N-dimethyl-formamide / 20 °C

7.1: 1H-tetrazole / dichloromethane / 20 °C

8.1: 3-chloro-benzenecarboperoxoic acid / 1.5 h / -78 - 20 °C

9.1: methanol; potassium carbonate / 1 h / 20 °C

10.1: 1H-tetrazole / dichloromethane / 20 °C

11.1: 3-chloro-benzenecarboperoxoic acid / -78 - 20 °C

12.1: trimethylsilyl bromide / toluene / 12 h / 20 °C

12.2: 1 h / 0 °C

With 2,6-dimethylpyridine; 1H-tetrazole; methanol; trimethylsilyl bromide; Thermomyces lanuginosus lipase; palladium on activated charcoal; tris(dimethylamino)sulfonium trimethylsilyldifluoride; hydrogen; potassium carbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene;

DOI:10.1039/d0sc06219g

Reference yield:

(-)-1D-1-O-acetyl-4,6-di-O-benzyl-myo-inositol (159802-98-9) → dipalmitoyl PtdIns4P (127996-98-9)

Guidance literature:

Multi-step reaction with 11 steps

1.1: toluene-4-sulfonic acid / dichloromethane / 18 h / 20 °C

2.1: palladium on activated charcoal; hydrogen / ethyl acetate / 2 h / 20 °C

3.1: 2,6-dimethylpyridine / tetrahydrofuran / -78 °C

4.1: toluene-4-sulfonic acid / dichloromethane / 18 h / 30 °C

5.1: tris(dimethylamino)sulfonium trimethylsilyldifluoride / N,N-dimethyl-formamide / 20 °C

6.1: 1H-tetrazole / dichloromethane / 20 °C

7.1: 3-chloro-benzenecarboperoxoic acid / 1.5 h / -78 - 20 °C

8.1: methanol; potassium carbonate / 1 h / 20 °C

9.1: 1H-tetrazole / dichloromethane / 20 °C

10.1: 3-chloro-benzenecarboperoxoic acid / -78 - 20 °C

11.1: trimethylsilyl bromide / toluene / 12 h / 20 °C

11.2: 1 h / 0 °C

With 2,6-dimethylpyridine; 1H-tetrazole; methanol; trimethylsilyl bromide; palladium on activated charcoal; tris(dimethylamino)sulfonium trimethylsilyldifluoride; hydrogen; potassium carbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene;

DOI:10.1039/d0sc06219g

upstream raw materials:

4,6-di-O-benzyl-myo-inositol

(-)-1D-1-O-acetyl-4,6-di-O-benzyl-myo-inositol

(+)-3-O-(4-methoxybenzyl)-1,2-di-O-hexadecanoyl-sn-glycerol

1,2-dipalmitoyl-sn-glycerol