ethyl 2-(3,4-dihydro-2H-chromen-4-yl)acetate

Base Information

• Chemical Name: ethyl 2-(3,4-dihydro-2H-chromen-4-yl)acetate
• CAS No.: 119304-96-0
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.268
• DSSTox Substance ID: DTXSID40557341
• Mol file: 119304-96-0.mol

Synonyms:119304-96-0;ethyl 2-(3,4-dihydro-2H-chromen-4-yl)acetate;ETHYL 2-(CHROMAN-4-YL)ACETATE;Ethyl2-(chroman-4-yl)acetate;ETHYL 2-(3,4-DIHYDRO-2H-1-BENZOPYRAN-4-YL)ACETATE;ethyl chroman-4-ylacetate;SCHEMBL3596582;ethyl (2-chrornan-4-yl)acetate;DTXSID40557341;UKJHGKSYAFMJHL-UHFFFAOYSA-N;MFCD11976262;AKOS037648532;BS-14463;CS-0161604;(+/-)-chroman-4-yl-acetic acid ethyl ester;F53805;EN300-7434878;Ethyl (3,4-dihydro-2H-1-benzopyran-4-yl)acetate

Chemical Property of ethyl 2-(3,4-dihydro-2H-chromen-4-yl)acetate

Chemical Property:

• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 220.109944368
• Heavy Atom Count: 16
• Complexity: 239

Purity/Quality:

99% ^*data from raw suppliers

ethyl2-(3,4-dihydro-2H-chromen-4-yl)acetate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)CC1CCOC2=CC=CC=C12

Technology Process of ethyl 2-(3,4-dihydro-2H-chromen-4-yl)acetate

There total 4 articles about ethyl 2-(3,4-dihydro-2H-chromen-4-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl (E)-2-(2,3-dihydro-4H-1-benzopyran-4-ylidene)acetate (121278-28-2) → ethyl 2-(3,4-dihydro-2H-1-benzopyran-4-yl)-ethanoate (119304-96-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; under 6000.6 Torr;

DOI:10.1039/c5cc01632k

Reference yield:

ethyl (E,Z)-(3,4-dihydro-2H-1-benzopyran-4-ylidene)acetate + pyrographite (7440-44-0) → ethyl 2-(3,4-dihydro-2H-1-benzopyran-4-yl)-ethanoate (119304-96-0)

Guidance literature:

palladium; In methanol;

Reference yield:

2,3-dihydro-4H-1-benzopyran-4-one (491-37-2) → ethyl 2-(3,4-dihydro-2H-1-benzopyran-4-yl)-ethanoate (119304-96-0)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1248/cpb.36.3453

upstream raw materials:

2,3-dihydro-4H-1-benzopyran-4-one

pyrographite

ethyl (E)-2-(2,3-dihydro-4H-1-benzopyran-4-ylidene)acetate

Downstream raw materials:

(±)-chroman-4-ylacetic acid

(chroman-4-yl)acetone

N-phenethyl-2-(chroman-4-yl)-1-methylethylamine