6,6-Bis(trifluormethyl)-3-cyclohexencarbaldehyd

Base Information

• Chemical Name: 6,6-Bis(trifluormethyl)-3-cyclohexencarbaldehyd
• CAS No.: 220865-82-7
• Molecular Formula: C₉H₈F₆O
• Molecular Weight: 246.152
• Mol file: 220865-82-7.mol

Synonyms:

Chemical Property of 6,6-Bis(trifluormethyl)-3-cyclohexencarbaldehyd

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,6-Bis(trifluormethyl)-3-cyclohexencarbaldehyd

There total 1 articles about 6,6-Bis(trifluormethyl)-3-cyclohexencarbaldehyd which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

buta-1,3-diene (106-99-0,130983-70-9,29406-96-0,9003-17-2) + 4,4,4-Trifluoro-3-(trifluoromethyl)-2-butenal (104291-39-6) → 6,6-Bis(trifluormethyl)-3-cyclohexencarbaldehyd (220865-82-7)

Guidance literature:

In diethyl ether; for 48h; Heating;

Reference yield: 44.0%

acetone (67-64-1) + 6,6-Bis(trifluormethyl)-3-cyclohexencarbaldehyd (220865-82-7) → 4-Hydroxy-4-<6,6-bis(trifluormethyl)-3-cyclohexenyl>-3-butanon (220865-93-0)

Guidance literature:

With potassium tert-butylate; In diethyl ether; for 12h; Heating;

Reference yield:

6,6-Bis(trifluormethyl)-3-cyclohexencarbaldehyd (220865-82-7) → 4-<6,6-Bis(trifluormethyl)-3-cyclohexenyl>-3-buten-2-on

Guidance literature:

Multi-step reaction with 2 steps

1: 44 percent / t-BuOK / diethyl ether / 12 h / Heating

2: 30percent HCl

With hydrogenchloride; potassium tert-butylate; In diethyl ether;

upstream raw materials:

buta-1,3-diene

4,4,4-Trifluoro-3-(trifluoromethyl)-2-butenal

Downstream raw materials:

4-Hydroxy-4-<6,6-bis(trifluormethyl)-3-cyclohexenyl>-3-butanon