1,4-Methanoanthracene,1,4-dihydro-9,10-dimethoxy-

Base Information

• Chemical Name: 1,4-Methanoanthracene,1,4-dihydro-9,10-dimethoxy-
• CAS No.: 52457-25-7
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.313
• DSSTox Substance ID: DTXSID10966885
• Nikkaji Number: J723.980G
• Mol file: 52457-25-7.mol

Synonyms:1,4-Methanoanthracene,1,4-dihydro-9,10-dimethoxy-;52457-25-7;Antrhracene, 1,4-dihydro-1,4-methano-9,10-dimethoxy-;Oprea1_123822;9,10-dimethoxy-1,4-dihydro-1,4-methanoanthracene;1,4-Methanoanthracene, 1,4-dihydro-9,10-dimethoxy-;DTXSID10966885;MVNKVWQSNVLBIV-UHFFFAOYSA-N;RCL T196711;AKOS024321902

Chemical Property of 1,4-Methanoanthracene,1,4-dihydro-9,10-dimethoxy-

Chemical Property:

• Vapor Pressure: 9.12E-06mmHg at 25°C
• Boiling Point: 384.3°C at 760 mmHg
• Flash Point: 156.6°C
• Density: 1.198g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 252.115029749
• Heavy Atom Count: 19
• Complexity: 344

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C2C3CC(C2=C(C4=CC=CC=C41)OC)C=C3

Technology Process of 1,4-Methanoanthracene,1,4-dihydro-9,10-dimethoxy-

There total 4 articles about 1,4-Methanoanthracene,1,4-dihydro-9,10-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,4,4a,9a-Tetrahydro-1,4-endomethylen-anthrachinon (24402-95-7,33741-23-0,127709-12-0) + methyl iodide (74-88-4) → 1,4-dihydro-9,10-dimethoxy-1,4-methanoanthracene (52457-25-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 3h; Ambient temperature;

DOI:10.1021/jo01312a019

Reference yield:

1,4,4a,9a-tetrahydro-1,4-methanoanthracene-9,10-dione (24402-95-7) → 1,4-Dihydro-1,4-methano-9,10-dimethoxyanthracene (52457-25-7)

Guidance literature:

Multi-step reaction with 2 steps

1: KOtBu

2: aq. NaOH

With sodium hydroxide; potassium tert-butylate;

Reference yield:

1,4,4a,9a-tetrahydro-1,4-methanoanthracene-9,10-dione (24402-95-7) + dimethyl sulfate (77-78-1) → 1,4-Dihydro-1,4-methano-9,10-dimethoxyanthracene (52457-25-7)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

1,4,4a,9a-tetrahydro-1,4-methanoanthracene-9,10-dione

dimethyl sulfate

1,4-dihydro-1,4-methanoanthracene-9,10-diol

1,4,4a,9a-Tetrahydro-1,4-endomethylen-anthrachinon

Downstream raw materials:

1,2,3,4-Tetrahydro-1,4-methano-9,10-dimethoxyanthracene

9,10-dimethoxy-1,4-methano-1,2,3,4-tetrahydroanthracene