4-Hydroxy-6-phenyl-N-2H-tetrazol-5-yl-2-pyridinecarboxamide

Base Information

Chemical Name:4-Hydroxy-6-phenyl-N-2H-tetrazol-5-yl-2-pyridinecarboxamide
CAS No.:78296-38-5
Molecular Formula:C₁₃H₁₀N₆O₂
Molecular Weight:282.261
Hs Code.:
DSSTox Substance ID:DTXSID001188039

Synonyms:SCHEMBL11298259;4-Hydroxy-6-phenyl-N-2H-tetrazol-5-yl-2-pyridinecarboxamide;DTXSID001188039;78296-38-5

Suppliers and Price of 4-Hydroxy-6-phenyl-N-2H-tetrazol-5-yl-2-pyridinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Hydroxy-6-phenyl-N-2H-tetrazol-5-yl-2-pyridinecarboxamide

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:282.08652358
Heavy Atom Count:21
Complexity:495

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)C=C(N2)C(=O)NC3=NNN=N3

Technology Process of 4-Hydroxy-6-phenyl-N-2H-tetrazol-5-yl-2-pyridinecarboxamide

There total 3 articles about 4-Hydroxy-6-phenyl-N-2H-tetrazol-5-yl-2-pyridinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2397-77-5
Ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate

: 78296-38-5
4-Hydroxy-6-phenyl-pyridine-2-carboxylic acid (1H-tetrazol-5-yl)-amide

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / NH₃ / ethanol / 16 h / 110 - 120 °C

2: 90 percent / 5 N NaOH / ethanol / 2 h / Heating

3: SOCl₂ / Ambient temperature

4: pyridine / 60 - 70 °C

With sodium hydroxide; thionyl chloride; ammonia; In pyridine; ethanol;
DOI:10.1248/cpb.30.4314

Reference yield:

: 85814-93-3
4-hydroxy-6-phenylpyridine-2-carboxamide

: 78296-38-5
4-Hydroxy-6-phenyl-pyridine-2-carboxylic acid (1H-tetrazol-5-yl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / 5 N NaOH / ethanol / 2 h / Heating

2: SOCl₂ / Ambient temperature

3: pyridine / 60 - 70 °C

With sodium hydroxide; thionyl chloride; In pyridine; ethanol;
DOI:10.1248/cpb.30.4314

Reference yield:

: 78296-37-4
4-hydroxy-6-phenylpyridine-2-carboxylic acid

: 78296-38-5
4-Hydroxy-6-phenyl-pyridine-2-carboxylic acid (1H-tetrazol-5-yl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / Ambient temperature

2: pyridine / 60 - 70 °C

With thionyl chloride; In pyridine;
DOI:10.1248/cpb.30.4314