5-{[2-(perfluorooctyl)ethyl]thiomethyl}-N-(2,4,6-trimethylphenyloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide

Base Information

• Chemical Name: 5-{[2-(perfluorooctyl)ethyl]thiomethyl}-N-(2,4,6-trimethylphenyloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide
• CAS No.: 1309763-38-9
• Molecular Formula: C₂₃H₁₈F₁₇N₃O₅S₃
• Molecular Weight: 835.584
• Mol file: 1309763-38-9.mol

Synonyms:

Chemical Property of 5-{[2-(perfluorooctyl)ethyl]thiomethyl}-N-(2,4,6-trimethylphenyloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-{[2-(perfluorooctyl)ethyl]thiomethyl}-N-(2,4,6-trimethylphenyloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide

There total 4 articles about 5-{[2-(perfluorooctyl)ethyl]thiomethyl}-N-(2,4,6-trimethylphenyloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

5-{[2-(perfluorooctyl)ethyl]thiomethyl}-1,3,4-oxadiazole-2-thione (1309763-33-4) + isocyanate de trimethyl-2,4,6 phenoxysulfonyle (17648-64-5) → 5-{[2-(perfluorooctyl)ethyl]thiomethyl}-N-(2,4,6-trimethylphenyloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide (1309763-38-9)

Guidance literature:

In acetone; at 20 ℃; for 0.25h;

DOI:10.1080/00397911.2010.494816

Reference yield:

1H,1H,2H,2H-Perfluorodecanethiol (34143-74-3) → 5-{[2-(perfluorooctyl)ethyl]thiomethyl}-N-(2,4,6-trimethylphenyloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide (1309763-38-9)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine / acetone / 0.17 h / 20 °C

2: hydrazine hydrate / methanol / Reflux

3: potassium hydroxide / ethanol; water / 8 h / Reflux

4: acetone / 0.25 h / 20 °C

With hydrazine hydrate; triethylamine; potassium hydroxide; In methanol; ethanol; water; acetone;

DOI:10.1080/00397911.2010.494816

Reference yield:

2-(perfluorooctyl)ethylthioacetohydrazide (1309763-31-2) → 5-{[2-(perfluorooctyl)ethyl]thiomethyl}-N-(2,4,6-trimethylphenyloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide (1309763-38-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol; water / 8 h / Reflux

2: acetone / 0.25 h / 20 °C

With potassium hydroxide; In ethanol; water; acetone;

DOI:10.1080/00397911.2010.494816

upstream raw materials:

5-{[2-(perfluorooctyl)ethyl]thiomethyl}-1,3,4-oxadiazole-2-thione

isocyanate de trimethyl-2,4,6 phenoxysulfonyle

2-(perfluorooctyl)ethylthioacetohydrazide

1H,1H,2H,2H-Perfluorodecanethiol