4-[⁽¹⁾-chloro-⁽²⁾-methylbutyl carboxy]-4'-biphenylcarboxyphenylferrocene

Base Information

• Chemical Name: 4-[⁽¹⁾-chloro-⁽²⁾-methylbutyl carboxy]-4'-biphenylcarboxyphenylferrocene
• CAS No.: 516479-93-9
• Molecular Formula: C₃₅H₃₁ClFeO₄
• Molecular Weight: 606.929
• Mol file: 516479-93-9.mol

Synonyms:

Chemical Property of 4-[⁽¹⁾-chloro-⁽²⁾-methylbutyl carboxy]-4'-biphenylcarboxyphenylferrocene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-[⁽¹⁾-chloro-⁽²⁾-methylbutyl carboxy]-4'-biphenylcarboxyphenylferrocene

There total 1 articles about 4-[⁽¹⁾-chloro-⁽²⁾-methylbutyl carboxy]-4'-biphenylcarboxyphenylferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-chloro-2-methylbutanecarboxylic acid (921-48-2) + 4-ferrocenylphenyl-4'-hydroxy-4-biphenylcarboxylate (516479-61-1) → 4-[(1)-chloro-(2)-methylbutyl carboxy]-4'-biphenylcarboxyphenylferrocene (516479-93-9)

Guidance literature:

With 4-dimethylaminopyridine; dicyclohexylcarbodiimide; In dichloromethane; under N2; soln. of dicyclohexylcarbodiimide in anhyd. CH2Cl2 added over 1 min to soln. of Fe complex, butanecarboxylic acid and 4-dimethylaminopyridine (molar ratio 4.3:3:3:1) in anhyd. CH2Cl2; stirred (room temp., 2wk); stirred under reflux for 1 wk; soln. filtered; solvent removed in vac.; purified by flash column chromy. (silica gel, C6H14-CH2Cl2); solvent removed from collected fractions; recrystd. from CH2Cl2-MeOH; elem. anal.;

DOI:10.1016/S0022-328X(02)02044-2

upstream raw materials:

1-chloro-2-methylbutanecarboxylic acid

4-ferrocenylphenyl-4'-hydroxy-4-biphenylcarboxylate