{4-[(Dimethylamino)methyl]phenyl}(phenyl)methanone

Base Information

Chemical Name:{4-[(Dimethylamino)methyl]phenyl}(phenyl)methanone
CAS No.:13991-01-0
Molecular Formula:C16H17NO
Molecular Weight:239.317
Hs Code.:
DSSTox Substance ID:DTXSID40591624
Wikidata:Q82485435

Synonyms:13991-01-0;{4-[(Dimethylamino)methyl]phenyl}(phenyl)methanone;(4-((Dimethylamino)methyl)phenyl)(phenyl)methanone;SCHEMBL2919154;DTXSID40591624

Suppliers and Price of {4-[(Dimethylamino)methyl]phenyl}(phenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of {4-[(Dimethylamino)methyl]phenyl}(phenyl)methanone

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:239.131014166
Heavy Atom Count:18
Complexity:260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CC1=CC=C(C=C1)C(=O)C2=CC=CC=C2

Technology Process of {4-[(Dimethylamino)methyl]phenyl}(phenyl)methanone

There total 10 articles about {4-[(Dimethylamino)methyl]phenyl}(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 124-40-3
dimethyl amine

: 32752-54-8
4-(bromomethyl)benzophenone

: 13991-01-0
4-dimethylaminomethylbenzophenone

Guidance literature:: In diethyl ether; water; at 20 ℃;
DOI:10.1002/anie.200703832

Reference yield: 83.0%

: (4-dimethylaminomethyl-phenyl)phenylmethanol

: 13991-01-0
4-dimethylaminomethylbenzophenone

Guidance literature:: With Jones reagent; In acetone; at 0 ℃;
DOI:10.1021/acs.joc.7b00563

Reference yield:

: 620-86-0
4-Benzylbenzoic acid

: 13991-01-0
4-dimethylaminomethylbenzophenone

Guidance literature:: Multi-step reaction with 4 steps

1: tert.-butylhydroperoxide; copper(II) bis(trifluoromethanesulfonate) / water / 20 h / 100 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 7 h / 0 °C / Inert atmosphere; Reflux

3: acetic acid; N-hydroxyphthalimide; oxygen; copper(II) acetate tetrahydrate / 22 h / 50 °C / 760.05 Torr / Schlenk technique

4: Jones reagent / acetone / 0 °C

With tert.-butylhydroperoxide; lithium aluminium tetrahydride; Jones reagent; N-hydroxyphthalimide; copper(II) acetate tetrahydrate; oxygen; copper(II) bis(trifluoromethanesulfonate); acetic acid; In tetrahydrofuran; water; acetone;
DOI:10.1021/acs.joc.7b00563