C₁₈H₂₄N₂

Base Information

• Chemical Name: C₁₈H₂₄N₂
• CAS No.: 1148155-19-4
• Molecular Formula: C₁₈H₂₄N₂
• Molecular Weight: 268.402
• Mol file: 1148155-19-4.mol

Synonyms:

Chemical Property of C₁₈H₂₄N₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₄N₂

There total 3 articles about C₁₈H₂₄N₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H22N4 → C18H24N2 (1148155-19-4)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; acetic acid; In methanol; at 20 ℃;

DOI:10.3987/COM-08-S(N)123

Reference yield:

L-tert-leucine methyl ester hydrochloride (63038-27-7,167223-43-0) → C18H24N2 (1148155-19-4)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether / 12 h / 0 - 20 °C

2: sodium azide; trifluoroacetic acid / 0 - 20 °C

3: hydrogen; palladium 10% on activated carbon / methanol; acetic acid / 1 h / 20 °C

With sodium azide; palladium 10% on activated carbon; hydrogen; trifluoroacetic acid; In methanol; diethyl ether; acetic acid; 1: |Grignard Reaction;

DOI:10.1016/j.tetlet.2016.11.030

Reference yield:

phenylmagnesium bromide (100-58-3) → C18H24N2 (1148155-19-4)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether / 12 h / 0 - 20 °C

2: sodium azide; trifluoroacetic acid / 0 - 20 °C

3: hydrogen; palladium 10% on activated carbon / methanol; acetic acid / 1 h / 20 °C

With sodium azide; palladium 10% on activated carbon; hydrogen; trifluoroacetic acid; In methanol; diethyl ether; acetic acid; 1: |Grignard Reaction;

DOI:10.1016/j.tetlet.2016.11.030

upstream raw materials:

L-tert-leucine methyl ester hydrochloride

phenylmagnesium bromide