2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid piperidine salt

Base Information

• Chemical Name: 2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid piperidine salt
• CAS No.: 866206-34-0
• Molecular Formula: C₅H₁₂N*C₄₈H₂₈N₅O₂Zn
• Molecular Weight: 858.33
• Mol file: 866206-34-0.mol

Synonyms:

Chemical Property of 2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid piperidine salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid piperidine salt

There total 2 articles about 2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid piperidine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

piperidine (110-89-4) + 2-formyl-5,10,15,20-tetraphenylporphyrinato zinc(II) (110350-65-7) + cyanoacetic acid (372-09-8) → 2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid piperidine salt (866206-34-0)

Guidance literature:

In acetonitrile; under N2 or Ar; shielded from ambient light; soln. of Zn porphyrin complex, cyanoacetic acid, and piperidine in CH3CN refluxed for 1 h; cooled to room temp.; ppt. collected by filtration; rinsed with CH3CN; recrystn. from CHCl3/5% MeOH/CH3CN;

DOI:10.1021/jp052877w

Reference yield:

2-formyl-5,10,15,20-tetraphenylporphyrine → 2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid piperidine salt (866206-34-0)

Guidance literature:

Multi-step reaction with 2 steps

1: chloroform; methanol

2: acetonitrile

In methanol; chloroform; acetonitrile;

DOI:10.1021/jp052877w

Reference yield: 93.0%

2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid piperidine salt (866206-34-0) + phosphoric acid (86119-84-8,7664-38-2) → 2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid (866206-33-9,911384-94-6)

Guidance literature:

In dimethylsulfoxide-d6; chloroform; water; under N2 or Ar; shielded from ambient light; Zn porphyrin complex dissolved in DMSO-d6; H2O and CHCl3 added; transfered to separating funnel; 2M H3PO4 (2.0 ml) added; vigorously shaken (pH 2.0); org. layer washed with H2O (150 ml) containing 2 M H3PO4 (1.0 ml); sepn.; CHCl3 removed with azeotrope distn. with CH3CN in vac.; pptn. with H2O;

DOI:10.1021/jp052877w

upstream raw materials:

piperidine

2-formyl-5,10,15,20-tetraphenylporphyrinato zinc(II)

cyanoacetic acid

Downstream raw materials:

2-cyano-3-(2'-(5',10',15',20'-tetraphenylporphyrinato zinc(II)yl))acrylic acid