6-Bromo-2,3-dihydro-1h-pyrrolo[1,2-a]benzimidazole

Base Information

Chemical Name:6-Bromo-2,3-dihydro-1h-pyrrolo[1,2-a]benzimidazole
CAS No.:59506-74-0
Molecular Formula:C₁₀H₉BrN₂
Molecular Weight:237.099
Hs Code.:
NSC Number:142134
DSSTox Substance ID:DTXSID20301263
Wikidata:Q82044975

Synonyms:59506-74-0;6-Bromo-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazole;6-bromo-2,3-dihydro-1h-pyrrolo[1,2-a]benzimidazole;NSC142134;DTXSID20301263;TQP0198;NSC-142134

Suppliers and Price of 6-Bromo-2,3-dihydro-1h-pyrrolo[1,2-a]benzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6-Bromo-2,3-dihydro-1h-pyrrolo[1,2-a]benzimidazole

Chemical Property:

Vapor Pressure:3.56E-06mmHg at 25°C
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:235.99491
Heavy Atom Count:13
Complexity:209

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC2=NC3=C(N2C1)C=CC(=C3)Br

Technology Process of 6-Bromo-2,3-dihydro-1h-pyrrolo[1,2-a]benzimidazole

There total 4 articles about 6-Bromo-2,3-dihydro-1h-pyrrolo[1,2-a]benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 5-bromo-2-(pyrrolidin-1-yl)aniline

: 59506-74-0
6-Brom-2,3-dihydro-1H-pyrrolo<1,2-a>benzimidazol

Guidance literature:: With dihydrogen peroxide; In water; ethyl acetate; for 2h; Reflux; Green chemistry;
DOI:10.1016/j.tetlet.2017.07.102

Reference yield: 47.0%

: 123-75-1
pyrrolidine

: 13125-68-3
1-bromo-3-nitrosobenzene

: 59506-74-0
6-Brom-2,3-dihydro-1H-pyrrolo<1,2-a>benzimidazol

Guidance literature:: With 2,4 dichlorobenzoic acid; In toluene; at 20 - 110 ℃; for 8.33h; Inert atmosphere;
DOI:10.1021/acs.orglett.7b00832

Reference yield:

: 591-19-5
m-Bromoaniline

: 59506-74-0
6-Brom-2,3-dihydro-1H-pyrrolo<1,2-a>benzimidazol

Guidance literature:: Multi-step reaction with 2 steps

1: Oxone / dichloromethane; water / 5 h / 20 °C / Inert atmosphere

2: 2,4 dichlorobenzoic acid / toluene / 8.33 h / 20 - 110 °C / Inert atmosphere

With Oxone; 2,4 dichlorobenzoic acid; In dichloromethane; water; toluene;
DOI:10.1021/acs.orglett.7b00832