3-(4-Bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde

Base Information

Chemical Name:3-(4-Bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde
CAS No.:618098-49-0
Molecular Formula:C₁₆H₁₀BrClN₂O
Molecular Weight:361.625
Hs Code.:
European Community (EC) Number:651-473-0
DSSTox Substance ID:DTXSID301167240
Mol file:618098-49-0.mol

Synonyms:618098-49-0;3-(4-BROMOPHENYL)-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE;DTXSID301167240;AKOS009307112;3-(4-Bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carboxaldehyde

Suppliers and Price of 3-(4-Bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(4-BROMOPHENYL)-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE 95.00%
10G
$ 7882.88

American Custom Chemicals Corporation
3-(4-BROMOPHENYL)-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE 95.00%
5G
$ 4244.63

American Custom Chemicals Corporation
3-(4-BROMOPHENYL)-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE 95.00%
1G
$ 1030.84

Total 2 raw suppliers

Chemical Property of 3-(4-Bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:359.96650
Heavy Atom Count:21
Complexity:354

Purity/Quality:

99% ^*data from raw suppliers

3-(4-BROMOPHENYL)-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NN(C=C2C=O)C3=CC=C(C=C3)Cl)Br

Technology Process of 3-(4-Bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde

There total 6 articles about 3-(4-Bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: C₁₄H₁₂BrClN₂

: 618098-49-0
3-(4-bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-formamide; at 0 - 70 ℃; for 3h;
DOI:10.1039/c5ra04995d

Reference yield: 79.0%

: C₁₄H₁₂BrClN₂

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 618098-49-0
3-(4-bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde

Guidance literature:: With trichlorophosphate;
DOI:10.2174/1570180813666161103145224

Reference yield:

: 1073-70-7
4-chlorophenylhydrazine hydrochloride

: 618098-49-0
3-(4-bromophenyl)-1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; sodium hydroxide / 1 h / 20 °C

2: trichlorophosphate / N,N-dimethyl-formamide / 3 h / 0 - 70 °C

With acetic acid; sodium hydroxide; trichlorophosphate; In N,N-dimethyl-formamide; 2: |Vilsmeier-Haack Formylation;
DOI:10.1039/c5ra04995d